Huntingtin HTT1a is generated in a CAG repeat-length-dependent manner in human tissues
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DOI: 10.1186/s10020-024-00801-2
Abstract: The disease-causing mutation in Huntington disease (HD) is a CAG trinucleotide expansion in the huntingtin (HTT) gene. The mutated CAG tract results in the production of a small RNA, HTT1a, coding for only exon 1… read more here.
Keywords: expression; repeat length; htt1a; cag repeat ... See more keywords