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Published in 2020 at "Molecular Genetics & Genomic Medicine"
DOI: 10.1002/mgg3.1352
Abstract: Abstract Background The short (s) allele of the 5‐HTTLPR polymorphism in the promoter region of the human serotonin transporter (5‐HTT) gene SLC6A4 has previously been associated with anxiety‐related personality dimensions. However, this relationship has not…
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Keywords:
anxiety related;
serotonin transporter;
anxiety;
httlpr rs25531 ... See more keywords
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Published in 2017 at "Journal of affective disorders"
DOI: 10.1016/j.jad.2016.08.055
Abstract: BACKGROUND A tri-allelic serotonin transporter promoter polymorphism (5-HTTLPR/rs25531) more effectively determines the levels of transcriptional efficacy than that with the bi-allelic 5-HTTLPR polymorphism in vitro. Both are reportedly associated with personality traits of negative emotionality,…
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Keywords:
serotonin transporter;
anxiety;
httlpr rs25531;
anxiety depression ... See more keywords
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Published in 2020 at "Neuropsychobiology"
DOI: 10.1159/000512699
Abstract: Introduction: Panic disorder (PD) has many comorbidities such as depression, bipolar disorder (BPD), and agoraphobia (AG). PD is a moderately heritable anxiety disorder whose pathogenesis is not well understood. Recently, a tri-allelic serotonin transporter (5-HTTLPR/rs25531)…
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Keywords:
rs25531 polymorphism;
httlpr rs25531;
disorder;
httlpr ... See more keywords