Lipid Accumulation in Hearts Transplanted From Nondiabetic Donors to Diabetic Recipients.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of the American College of Cardiology"
DOI: 10.1016/j.jacc.2020.01.018
Abstract: BACKGROUND Early pathogenesis of diabetic cardiomyopathy (DMCM) may involve lipotoxicity of cardiomyocytes in the context of hyperglycemia. There are many preclinical studies of DMCM pathogenesis, but the human evidence is still poorly understood. OBJECTIVES By… read more here.
Keywords: htx recipients; accumulation; lipid accumulation; accumulation hearts ... See more keywords
Sodium/glucose cotransporter 2 (SGLT2) inhibitors improve cardiac function by reducing JunD expression in human diabetic hearts.
Sign Up to like & getrecommendations! Published in 2021 at "Metabolism: clinical and experimental"
DOI: 10.1016/j.metabol.2021.154936
Abstract: BACKGROUND The pathogenesis of experimental diabetic cardiomyopathy may involve the activator protein 1 (AP-1) member, JunD. Using non-diabetic heart transplant (HTX) in recipients with diabetes, we examined the effects of the diabetic milieu (hyperglycemia and… read more here.
Keywords: htx recipients; jund expression; jund; recipients diabetes ... See more keywords
Heart rate response during cardiopulmonary exercise in heart transplant recipients
Sign Up to like & getrecommendations! Published in 2020 at "European Heart Journal"
DOI: 10.1093/ehjci/ehaa946.1112
Abstract: Denervation at heart transplant (HTx) results in attenuated heart rate (HR) control and limited exercise tolerance. The aim of this study was to assess longitudinal changes in the HR response to exercise in HTx recipients.… read more here.
Keywords: htx recipients; heart transplant; exercise; response ... See more keywords
Sudden cardiac death after heart transplantation: a population-based study
Sign Up to like & getrecommendations! Published in 2023 at "Europace"
DOI: 10.1093/europace/euad126
Abstract: Abstract Aims The epidemiology of sudden cardiac death (SCD) after heart transplantation (HTx) remains imprecisely described. We aimed to assess the incidence and determinants of SCD in a large cohort of HTx recipients, compared with… read more here.
Keywords: htx; death; htx recipients; risk ... See more keywords
T Cell and Antibody Response Following Double Dose of BNT162b2 mRNA Vaccine in SARS-CoV-2 Naïve Heart Transplant Recipients
Sign Up to like & getrecommendations! Published in 2022 at "Diagnostics"
DOI: 10.3390/diagnostics12092148
Abstract: Introduction: Preliminary studies have suggested a low post-vaccination antibody response against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in heart transplant(HTx)recipients. Although many studies have focused on the role of antibodies in vaccine-induced protection against… read more here.
Keywords: cell response; htx recipients; heart; response ... See more keywords