Huaier extract restrains the proliferative potential of endocrine-resistant breast cancer cells through increased ATM by suppressing miR-203
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-07550-9
Abstract: Endocrine therapy is one of the main treatments for breast cancer patients in the early stages. Tamoxifen and fulvestrant are the major drugs of endocrine therapy for breast cancer patients. However, acquired drug resistance often… read more here.
Keywords: huaier extract; endocrine resistant; breast cancer;
Effects of Huaier Extract on Ameliorating Colitis-Associated Colorectal Tumorigenesis in Mice
Sign Up to like & getrecommendations! Published in 2020 at "OncoTargets and therapy"
DOI: 10.2147/ott.s253598
Abstract: Background Huaier extract has been a part of traditional Chinese medicine (TCM) for roughly 1600 years and may serve as a potential anti-cancer drug as it is associated with good efficacy and low toxicity. Individuals… read more here.
Keywords: tumorigenesis; mice; colitis associated; huaier extract ... See more keywords
Huaier Extract Induces Apoptosis in Hepatoblastoma Cells Via the MEK/ERK Signaling Pathway
Sign Up to like & getrecommendations! Published in 2020 at "In Vivo"
DOI: 10.21873/invivo.12051
Abstract: Background/Aim: Huaier extract, whose main active constituent is the proteoglycan, has anti-tumor activity in several types of malignancies. In this study, we aimed to elucidate the effect of Huaier extract in hepatoblastoma cells. Materials and… read more here.
Keywords: apoptosis hepatoblastoma; hepatoblastoma cells; mek; huaier extract ... See more keywords
Huaier Extract Inhibits Prostate Cancer Growth via Targeting AR/AR-V7 Pathway
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2021.615568
Abstract: The androgen receptor (AR) plays a pivotal role in prostatic carcinogenesis, and it also affects the transition from hormone sensitive prostate cancer (HSPC) to castration-resistant prostate cancer (CRPC). Particularly, the persistent activation of the androgen… read more here.
Keywords: androgen; huaier extract; via targeting; prostate cancer ... See more keywords