Explore the effects of Huang‐Lian‐Jie‐Du‐Tang on Alzheimer's disease by UPLC‐QTOF/MS‐based plasma metabolomics study
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Pharmaceutical and Biomedical Analysis"
DOI: 10.1016/j.jpba.2017.12.053
Abstract: Graphical abstract Figure. No caption available. HighlightsThe underlying mechanism of HLJDT was explored by valid UPLC–MS‐based metabolomics.Memory amelioration and reduced neuroinflammation were observed in HLJDT group mice.Callback of lipid metabolic disorder indicates the effects of… read more here.
Keywords: huang lian; metabolism; alzheimer disease; lian jie ... See more keywords
Explore of the beneficial effects of Huang-Lian-Jie-Du Decoction on diabetic encephalopathy in db/db mice by UPLC-Q-Orbitrap HRMS/MS based untargeted metabolomics analysis.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of pharmaceutical and biomedical analysis"
DOI: 10.1016/j.jpba.2020.113652
Abstract: Diabetic encephalopathy (DE) is a severe diabetic complication with cognitive dysfunction. Huang-Lian-Jie-Du Decoction (HLJDD), a famous traditional Chinese formula, is effective for the treatment of diabetes mellitus and Alzheimer's disease in clinical practices, however, the… read more here.
Keywords: diabetic encephalopathy; huang lian; analysis; lian jie ... See more keywords
Metabonomics delineates allergic reactions induced by Shuang-huang-lian injection in rats using ultra performance liquid chromatography-mass spectrometry.
Sign Up to like & getrecommendations! Published in 2018 at "Chinese journal of natural medicines"
DOI: 10.1016/s1875-5364(18)30101-8
Abstract: Shuang-huang-lian Injection (SHLI) is the first successfully developed drug from traditional Chinese medicine (TCM) powder for injection, since its use for the treatment of acute respiratory tract infection, pneumonia, influenza, etc. At the same time,… read more here.
Keywords: lian injection; huang lian; allergic reaction; shuang huang ... See more keywords
A Preliminary Inquiry Into the Potential Mechanism of Huang-Lian-Jie-Du Decoction in Treating Rheumatoid Arthritis via Network Pharmacology and Molecular Docking
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2021.740266
Abstract: Huang-Lian-Jie-Du decoction (HLJDD) has been widely applied to treat inflammation-associated diseases for thousands of years in China. However, the concrete molecular mechanism of HLJDD in the treatment of rheumatoid arthritis (RA) remains unclear. In this… read more here.
Keywords: molecular docking; network; pharmacology; huang lian ... See more keywords
Benefits of Huang Lian mediated by gut microbiota on HFD/STZ-induced type 2 diabetes mellitus in mice
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2023.1120221
Abstract: Background Huang Lian (HL), one of the traditional Chinese medicines (TCMs) that contains multiple active components including berberine (BBR), has been used to treat symptoms associated with diabetes for thousands of years. Compared to the… read more here.
Keywords: gut; gut microbiota; huang lian; type diabetes ... See more keywords