The ubiquitin‐like protein Hub1/UBL‐5 functions in pre‐mRNA splicing in Caenorhabditis elegans
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DOI: 10.1002/1873-3468.14555
Abstract: The ubiquitin‐like protein Hub1/UBL‐5 associates with proteins non‐covalently. Hub1 promotes alternative splicing and splicing of precursor mRNAs with weak introns in yeast and mammalian cells; however, its splicing function has remained elusive in multicellular organisms.… read more here.
Keywords: hub1; protein hub1; ubiquitin like; caenorhabditis elegans ... See more keywords
Computer- and NMR-Aided Design of Small-Molecule Inhibitors of the Hub1 Protein
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DOI: 10.3390/molecules27238282
Abstract: By binding to the spliceosomal protein Snu66, the human ubiquitin-like protein Hub1 is a modulator of the spliceosome performance and facilitates alternative splicing. Small molecules that bind to Hub1 would be of interest to study… read more here.
Keywords: computer nmr; small molecule; hub1; hub1 protein ... See more keywords