Exosomes Derived from TIMP2-Modified Human Umbilical Cord Mesenchymal Stem Cells Enhance the Repair Effect in Rat Model with Myocardial Infarction Possibly by the Akt/Sfrp2 Pathway
Sign Up to like & getrecommendations! Published in 2019 at "Oxidative Medicine and Cellular Longevity"
DOI: 10.1155/2019/1958941
Abstract: Exosomes derived from human umbilical cord mesenchymal stem cells (hucMSCs) are a promising new therapeutic option for myocardial infarction (MI). The tissue matrix metalloproteinase inhibitor 2, also known as TIMP2, is a member of the… read more here.
Keywords: umbilical cord; huc exotimp2; exosomes derived; human umbilical ... See more keywords
Cryopreserved human umbilical cord as a meningeal patch during in utero spina bifida repair in a modified ovine model.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of neurosurgery"
DOI: 10.3171/2023.2.jns222928
Abstract: OBJECTIVE Despite in utero spina bifida (SB) repair, more than two-thirds of patients with SB are unable to ambulate independently, and 1 in 4 children need surgery for tethered cord by school age. The objective… read more here.
Keywords: cord; meningeal patch; spinal cord; huc ... See more keywords
Therapeutic Effects of Insulin-Producing Human Umbilical Cord-Derived Mesenchymal Stem Cells in a Type 1 Diabetes Mouse Model
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DOI: 10.3390/ijms23136877
Abstract: In patients with type 1 diabetes (T1D), compromised pancreatic β-cell functions are compensated through daily insulin injections or the transplantation of pancreatic tissue or islet cells. However, both approaches are associated with specific challenges. The… read more here.
Keywords: umbilical cord; mesenchymal stem; type diabetes; human umbilical ... See more keywords
Histological Profiling of the Human Umbilical Cord: A Potential Alternative Cell Source in Tissue Engineering
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DOI: 10.3390/jpm12040648
Abstract: The embryonic development of the human umbilical cord (hUC) is complex, and different regions can be identified in this structure. The aim of this work is to characterize the hUC at in situ and ex… read more here.
Keywords: cell; tissue engineering; umbilical cord; human umbilical ... See more keywords
Phenotype Characteristics and Osteogenic Differentiation Potential of Human Mesenchymal Stem Cells Derived from Amnion Membrane (HAMSCs) and Umbilical Cord (HUC-MSCs)
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DOI: 10.5455/aim.2019.27.72-77
Abstract: Introduction: Human amnion membrane mesenchymal stem cells (hAMSCs) and human umbilical cord mesenchymal stem cells (hUC-MSCs) are potential, non invasive sources of stem cells used for bone tissue engineering. Phenotyping characterization is an extremely important… read more here.
Keywords: huc mscs; differentiation; hamscs; passage ... See more keywords
hUC-MSC-mediated recovery of subacute spinal cord injury through enhancing the pivotal subunits β3 and γ2 of the GABAA receptor
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DOI: 10.7150/thno.72015
Abstract: Rationale: Spinal cord injury (SCI) remains an incurable neurological disorder leading to permanent and profound neurologic deficits and disabilities. Human umbilical cord-derived mesenchymal stem cells (hUC-MSCs) are particularly appealing in SCI treatment to curtail damage,… read more here.
Keywords: sci; spinal cord; huc; huc msc ... See more keywords