LAUSR

About LAUSR
Donate
Contact Us

Follow us:

You are not signed in:

Sign Up!


   Articles with "huc mscs" as a keyword



Photo by art_almighty from unsplash

hUC‐MSCs exosomal miR‐451 alleviated acute lung injury by modulating macrophage M2 polarization via regulating MIF‐PI3K‐AKT signaling pathway

Sign Up to like & get
recommendations! Published in 2022 at "Environmental Toxicology"

DOI: 10.1002/tox.23639

Abstract: In the previous study, we have proved that exosomal miR‐451 from human umbilical cord mesenchymal stem cells (hUC‐MSCs) attenuated burn‐induced acute lung injury (ALI). However, the mechanism of exosomal miR‐451 in ALI remains unclear. Therefore,… read more here.

Keywords: mir 451; macrophage polarization; huc mscs; exosomal mir ... See more keywords
Photo by hakannural from unsplash

Intra-articular injection of hUC-MSCs expressing miR-140-5p induces cartilage self-repairing in the rat osteoarthritis

Sign Up to like & get
recommendations! Published in 2019 at "Journal of Bone and Mineral Metabolism"

DOI: 10.1007/s00774-019-01055-3

Abstract: Introduction Currently, osteoarthritis (OA) receives global increasing attention because it associates severe joint pain and serious disability. Stem cells intra-articular injection therapy showed a potential therapeutic superiority to reduce OA development and to improve treating… read more here.

Keywords: huc mscs; articular injection; mscs; intra articular ... See more keywords
Photo by cdc from unsplash

Resveratrol promotes hUC-MSCs engraftment and neural repair in a mouse model of Alzheimer’s disease

Sign Up to like & get
recommendations! Published in 2018 at "Behavioural Brain Research"

DOI: 10.1016/j.bbr.2017.10.032

Abstract: ABSTRACT Mesenchymal stem cell transplantation is a promising therapeutic approach for Alzheimer's disease (AD). However, poor engraftment and limited survival rates are major obstacles for its clinical application. Resveratrol, an activator of silent information regulator… read more here.

Keywords: huc mscs; resveratrol; alzheimer disease; mscs engraftment ... See more keywords
Photo by sheylina from unsplash

Decline of p300 contributes to cell senescence and growth inhibition of hUC-MSCs through p53/p21 signaling pathway.

Sign Up to like & get
recommendations! Published in 2019 at "Biochemical and biophysical research communications"

DOI: 10.1016/j.bbrc.2019.05.061

Abstract: Human umbilical cord-derived mesenchymal stromal cells (hUC-MSCs) in vitro expansion for long term may undergo epigenetic and genetic alterations that subsequently induce cellular senescence and associated growth inhibition. Increasing evidence implicated that aberrant histone acetylation modulates… read more here.

Keywords: p53 p21; huc mscs; senescence; inhibition ... See more keywords
Photo from wikipedia

Human Umbilical Cord Mesenchymal Stem Cells Attenuate Podocyte Injury under High Glucose via TLR2 and TLR4 Signaling.

Sign Up to like & get
recommendations! Published in 2021 at "Diabetes research and clinical practice"

DOI: 10.1016/j.diabres.2021.108702

Abstract: AIMS This research aimed to investigate the effects of high glucose(HG) on the innate immunity of podocytes and diabetic nephropathy (DN) mice via Toll like receptor (TLR) signaling, and explore the protective effectsof human umbilical… read more here.

Keywords: huc mscs; umbilical cord; tlr2 tlr4; human umbilical ... See more keywords
Photo by kellysikkema from unsplash

Transplantation of hUC-MSCs seeded collagen scaffolds reduces scar formation and promotes functional recovery in canines with chronic spinal cord injury

Sign Up to like & get
recommendations! Published in 2017 at "Scientific Reports"

DOI: 10.1038/srep43559

Abstract: Spinal cord injury (SCI) can lead to locomotor deficits, and the repair of chronic SCI is considered one of the most challenging clinical problems. Although extensive studies have evaluated treatments for acute SCI in small… read more here.

Keywords: huc mscs; scar; cord; neuroregen scaffold ... See more keywords

Human umbilical cord-mesenchymal stem cells-derived exosomes carrying microRNA-15a-5p possess therapeutic effects on Wilms tumor via regulating septin 2

Sign Up to like & get
recommendations! Published in 2022 at "Bioengineered"

DOI: 10.1080/21655979.2022.2037379

Abstract: ABSTRACT The exact mechanism of miR-15a-5p shuttled by human umbilical cord-mesenchymal stem cell-derived exosomes (hUC-MSCs-Exo) in Wilms tumor (WT) was estimated. WT tissues were collected clinically. miR-15a-5p and septin 2 (SEPT2) expression levels were examined… read more here.

Keywords: mscs exo; huc mscs; mir 15a; 401 cells ... See more keywords
Photo by amandavickcreative from unsplash

Mesenchymal stem cells promote wound healing and effects on expression of matrix metalloproteinases-8 and 9 in the wound tissue of diabetic rats.

Sign Up to like & get
recommendations! Published in 2022 at "Stem cells and development"

DOI: 10.1089/scd.2021.0218

Abstract: Diabetic foot ulcer (DFU) is a multifactorial complication of diabetes, mainly manifested as infection, ulcer or destruction of deep tissue and there is currently no effective treatment. Several pre-clinical and clinical studies have proved that… read more here.

Keywords: huc mscs; stem cells; wound healing; expression ... See more keywords
Photo by kellysikkema from unsplash

Application of HUC-MSCs in Rat SCI Model.

Sign Up to like & get
recommendations! Published in 2023 at "ASAIO journal"

DOI: 10.1097/mat.0000000000001938

Abstract: The treatment of spinal cord injury (SCI) is a hot topic in clinic. In this study, female rats were selected and randomly divided into four groups (normal, sham, SCI, and mesenchymal stem cells [MSCs] groups).… read more here.

Keywords: cord; huc mscs; sci; model ... See more keywords
Photo from wikipedia

Repairing and Analgesic Effects of Umbilical Cord Mesenchymal Stem Cell Transplantation in Mice with Spinal Cord Injury

Sign Up to like & get
recommendations! Published in 2020 at "BioMed Research International"

DOI: 10.1155/2020/7650354

Abstract: Transplantation of human umbilical cord mesenchymal stem cells (hUC-MSCs) into spinal cord injury (SCI) may alleviate neuropathic pain and promote functional recovery. The underlying mechanism likely involves activation of glial cells and regulation of inflammatory… read more here.

Keywords: huc mscs; sci; cord; group ... See more keywords
Photo by thinkmagically from unsplash

Human Umbilical Cord-Mesenchymal Stem Cells Survive and Migrate within the Vitreous Cavity and Ameliorate Retinal Damage in a Novel Rat Model of Chronic Glaucoma

Sign Up to like & get
recommendations! Published in 2021 at "Stem Cells International"

DOI: 10.1155/2021/8852517

Abstract: Glaucoma is the leading cause of irreversible blindness worldwide, and pathologically elevated intraocular pressure (IOP) is the major risk factor. Neuroprotection is one of the potential therapies for glaucomatous retinal damage. Intravitreal mesenchymal stem cell… read more here.

Keywords: huc mscs; retinal damage; rat model; vitreous cavity ... See more keywords