Clinical Trial of Human Umbilical Cord Blood‐Derived Stem Cells for the Treatment of Moderate‐to‐Severe Atopic Dermatitis: Phase I/IIa Studies
Sign Up to like & getrecommendations! Published in 2017 at "STEM CELLS"
DOI: 10.1002/stem.2401
Abstract: Mesenchymal stem cells (MSCs) have been proven to be therapeutically effective against atopic dermatitis (AD) in preclinical studies. However, the safety and efficacy of MSCs against AD have not yet been investigated in a clinical… read more here.
Keywords: atopic dermatitis; stem cells; score; hucb mscs ... See more keywords
Repeated intramuscular transplantations of hUCB-MSCs improves motor function and survival in the SOD1 G93A mice through activation of AMPK
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DOI: 10.1038/s41598-020-58221-1
Abstract: Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease that is characterized by loss of motor neurons and degeneration of neuromuscular junctions. To improve disease progression, previous studies have suggested many options that have shown… read more here.
Keywords: repeated intramuscular; muscle; hucb mscs; transplantation ... See more keywords
Immunomodulatory Effect of Epidermal Growth Factor Secreted by Human Umbilical Cord Blood-Derived Mesenchymal Stem Cells on Atopic Dermatitis
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Stem Cells"
DOI: 10.15283/ijsc21173
Abstract: Background and Objectives Human mesenchymal stem cells (MSCs) are emerging as a treatment for atopic dermatitis (AD), a chronic inflammatory skin disorder that affects a large number of people across the world. Treatment of AD… read more here.
Keywords: hucb mscs; stem cells; effect; mscs ... See more keywords
Protective effects of human umbilical cord blood-derived mesenchymal stem cells against dexamethasone-induced apoptotic cell death in hair follicles
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DOI: 10.3892/ijmm.2019.4447
Abstract: Alopecia is a common and distressing condition, and developing new therapeutic agents to prevent hair loss is important. Human umbilical cord blood-derived mesenchymal stem cells (hUCB-MSCs) have been studied intensively in regenerative medicine. However, the… read more here.
Keywords: medicine; hair; hair loss; hucb mscs ... See more keywords
Disease-specific primed human adult stem cells effectively ameliorate experimental atopic dermatitis in mice
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DOI: 10.7150/thno.32945
Abstract: Although human mesenchymal stem cells (hMSCs) hold considerable promise as an alternative therapeutic reagent for allergic disorders including atopic dermatitis (AD), the strategy for enhancing hMSC-based therapy remains challenging. We sought to investigate whether preconditioning… read more here.
Keywords: atopic dermatitis; stem; stem cells; hucb mscs ... See more keywords