Human Umbilical Cord Mesenchymal Stem Cell-Derived Exosome Repairs Endometrial Epithelial Cells Injury Induced by Hypoxia via Regulating miR-663a/CDKN2A Axis
Sign Up to like & getrecommendations! Published in 2022 at "Oxidative Medicine and Cellular Longevity"
DOI: 10.1155/2022/3082969
Abstract: Aim Thin endometrium remains a severe clinical challenge with no effective therapy to date. We aimed at exploring the role and molecular mechanism of human umbilical cord mesenchymal stem cell- (hucMSC-) derived exosomes (hucMSC-Ex) in… read more here.
Keywords: cell; hucmsc; mir 663a; expression ... See more keywords
hucMSC-derived exosomes protect ovarian reserve and restore ovarian function in cisplatin treated mice.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of biomedical research"
DOI: 10.7555/jbr.36.20220166
Abstract: Anti-cancer therapy often causes premature ovarian insufficiency and infertility as the ovarian follicle reserve is extremely sensitive to chemotherapy drugs, such as cisplatin. Various fertility preservation methods have been explored for women, especially prepubertal girls… read more here.
Keywords: function; hucmsc; reserve; derived exosomes ... See more keywords