P064 Investigating the genotoxic effect of reduced glutathione, n-acetylcysteine, human umbilical cord-derived mesenchymal stem cell exosomes and let-7 miRNA mimics in human lymphocytes and EpiIntestinal cells
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Crohn's and Colitis"
DOI: 10.1093/ecco-jcc/jjad212.0194
Abstract: The current treatments for IBD frequently do not provide sufficient control over the disease, warranting the investigation of alternative therapeutic options with minimal risk of side effects. In IBD, the overgeneration and insufficient removal of… read more here.
Keywords: dna damage; hucmsc exo; gsh nac; epiintestinal cells ... See more keywords
Exosomes containing miR-148a-3p derived from mesenchymal stem cells suppress epithelial-mesenchymal transition in lens epithelial cells
Sign Up to like & getrecommendations! Published in 2025 at "Stem Cells Translational Medicine"
DOI: 10.1093/stcltm/szae091
Abstract: Abstract Epithelial-mesenchymal transition (EMT) of lens epithelial cells (LECs) is responsible for the development of fibrotic cataracts, which contribute to severe visual impairment. Recent evidence has shown that mesenchymal stem cell-derived exosomes (MSC-Exo) can attenuate… read more here.
Keywords: mir 148a; exo; lecs emt; hucmsc exo ... See more keywords
Comparison of efficacy of exosomes derived from human umbilical cord blood mesenchymal stem cells in treating mouse acute lung injury via different routes
Sign Up to like & getrecommendations! Published in 2025 at "Frontiers in Pediatrics"
DOI: 10.3389/fped.2025.1560915
Abstract: Objective To investigate the therapeutic efficacy of human umbilical cord blood mesenchymal stem cell-derived exosomes (hUCMSC-Exo) in a lipopolysaccharide (LPS)-induced acute lung injury (ALI) mouse model and compare the effects of different administration routes. Methods… read more here.
Keywords: dose; lung injury; hucmsc exo; efficacy ... See more keywords