A Single -195 C < G HBG1 Promoter Mediated By CRISPR/Cas9 Genome Editing Induces Fetal Hemoglobin Synthesis in Hudep-2
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DOI: 10.1182/blood-2018-99-118534
Abstract: Sickle cell disease (SCD) is a serious condition, chronic and undoubtedly represents a public health problem worldwide. SCD is caused by a point mutation in codon 6 of the β globin gene resulting in the… read more here.
Keywords: crispr cas9; hbg1; hudep; hpfh ... See more keywords