Vitamin K3 chloroderivative (VKT-2) inhibits HDAC6, activates autophagy and apoptosis and inhibits aggresome formation in hepatocellular carcinoma cells.
Sign Up to like & getrecommendations! Published in 2020 at "Biochemical pharmacology"
DOI: 10.1016/j.bcp.2020.114176
Abstract: Epigenetics plays a vital role in regulating gene expression and determining the specific phenotypes of eukaryotic cells. Histone deacetylases (HDACs) are important epigenetic regulatory proteins effecting multiple biological functions. Particularly, HDAC6 has become a promising… read more here.
Keywords: vkt; huh; vkt inhibits; inhibits hdac6 ... See more keywords
Modulating the Mechanical Resonance of Huh-7 Cells Based on Elasticity of Adhesion Proteins.
Sign Up to like & getrecommendations! Published in 2023 at "IEEE transactions on nanobioscience"
DOI: 10.1109/tnb.2023.3235645
Abstract: The atomic force microscope (AFM) has been used in cell biology for a decade. AFM is a unique tool for investigating the viscoelastic characteristics of live cells in culture and mapping the spatial distribution of… read more here.
Keywords: cell; afm; huh; geometry ... See more keywords
Optimization of Canalicular ABC Transporter Function in HuH-7 Cells by Modification of Culture Conditions
Sign Up to like & getrecommendations! Published in 2019 at "Drug Metabolism and Disposition"
DOI: 10.1124/dmd.119.087676
Abstract: Human hepatoma cell lines are useful for evaluation of drug-induced hepatotoxicity, hepatic drug disposition, and drug-drug interactions. However, their applicability is compromised by aberrant expression of hepatobiliary transporters. This study was designed to evaluate whether… read more here.
Keywords: canalicular abc; huh; drug; huh cells ... See more keywords
Cytotoxic effects of Lavandula angustifolia seed extracts on the viability of Huh-7 and Chang liver cells
Sign Up to like & getrecommendations! Published in 2022 at "PLoS ONE"
DOI: 10.1371/journal.pone.0267499
Abstract: Flowering plants are valuable in numerous ways, including food/feed supply for living organisms, fuel production, and medicinal uses. Several plant extracts/products are used to treat variety of serious ailments in human and animals. Lavandula angustifolia… read more here.
Keywords: liver; seed extracts; huh; chang ... See more keywords