Articles with "huh7 cells" as a keyword



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SARS-CoV-2 promote autophagy to suppress type I interferon response

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Published in 2021 at "Signal Transduction and Targeted Therapy"

DOI: 10.1038/s41392-021-00574-8

Abstract: Dear Editor, The outbreak of SARS-CoV-2 leads global epidemic with high morbidity and mortality. However, the pathophysiology of this deadly virus is complex and largely unknown. Autophagy is a highly conserved homeostatic process that allows… read more here.

Keywords: lc3; supplementary fig; sars cov; huh7 cells ... See more keywords
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Upregulation of PD-L1 expression promotes epithelial-to-mesenchymal transition in sorafenib-resistant hepatocellular carcinoma cells

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Published in 2020 at "Gastroenterology Report"

DOI: 10.1093/gastro/goaa049

Abstract: Abstract Background The epithelial-to-mesenchymal transition (EMT) status is associated with programmed death-1 ligand 1 (PD-L1) expression in various cancers. However, the role and molecular mechanism of PD-L1 in the EMT of sorafenib-resistant hepatocellular carcinoma (HCC)… read more here.

Keywords: hcc; sorafenib resistant; hepg2 huh7; huh7 cells ... See more keywords
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Cancer-associated fibroblasts endow stem-like qualities to liver cancer cells by modulating autophagy

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Published in 2019 at "Cancer Management and Research"

DOI: 10.2147/cmar.s197634

Abstract: Purpose Both cancer-associated fibroblasts (CAFs) and liver cancer stem cells (LCSCs) play an important part in the tumorigenesis, development and metastasis of hepatocellular carcinoma (HCC). Moreover, the stem-like properties in HCC cells could be promoted… read more here.

Keywords: autophagy; hcc; associated fibroblasts; cancer associated ... See more keywords

A novel strategy of transferring NIS protein to cells using extracellular vesicles leads to increase in iodine uptake and cytotoxicity

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Published in 2019 at "International Journal of Nanomedicine"

DOI: 10.2147/ijn.s189738

Abstract: Background This study was designed to explore a novel approach for transferring NIS protein to cells using extracellular vesicle (EV) and enhancing iodine avidity in hepatocellular carcinoma (HCC) cells. Methods We transfected the HCC cells… read more here.

Keywords: nis protein; protein cells; huh7 cells; protein ... See more keywords
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Instability of the NS1 Glycoprotein from La Reunion 2018 Dengue 2 Virus (Cosmopolitan-1 Genotype) in Huh7 Cells Is Due to Lysine Residues on Positions 272 and 324

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Published in 2021 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms22041951

Abstract: La Reunion island in the South West Indian Ocean is now endemic for dengue following the introduction of dengue virus serotype 2 (DENV-2) cosmopolitan-I genotype in 2017. DENV-2 infection causes a wide spectrum of clinical… read more here.

Keywords: dengue virus; reunion; huh7 cells; dengue ... See more keywords
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Paeonol-mediated apoptosis of hepatocellular carcinoma cells by NF-κB pathway

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Published in 2019 at "Oncology Letters"

DOI: 10.3892/ol.2018.9730

Abstract: The aim of the study was to investigate the effect of paeonol on the apoptosis of hepatocellular carcinoma cells and to explore the possible mechanism of its effect. During the experiment, the human hepatoma (Huh7)… read more here.

Keywords: apoptosis; group group; group; huh7 cells ... See more keywords