Long non‐coding RNA HULC stimulates the epithelial–mesenchymal transition process and vasculogenic mimicry in human glioblastoma
Sign Up to like & getrecommendations! Published in 2021 at "Cancer Medicine"
DOI: 10.1002/cam4.4083
Abstract: Long non‐coding RNA (lncRNA) HULC (highly upregulated in liver cancer) is considered as an oncogenic factor for various malignant tumors. This study aimed to reveal the role of lncRNA HULC in the malignant behavior of… read more here.
Keywords: mesenchymal transition; hulc; long non; non coding ... See more keywords
Metformin inhibits tumorigenesis in HBV‐induced hepatocellular carcinoma by suppressing HULC overexpression caused by HBX
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.26555
Abstract: We aimed to understand whether metformin imposes the inhibitory effect on the HBV‐associated tumorigenesis by regulating the HULC and its downstream signaling pathway. Luciferase assay, RT‐PCR, and Western‐blot, MTT and flow cytometry analysis were performed… read more here.
Keywords: hulc; tumorigenesis; hbv; metformin ... See more keywords
The association of lncRNA-HULC polymorphisms with hepatocellular cancer risk and prognosis.
Sign Up to like & getrecommendations! Published in 2018 at "Gene"
DOI: 10.1016/j.gene.2018.05.096
Abstract: BACKGROUND Genetic polymorphisms in lncRNA HULC may affect the susceptibility and clinical outcome of cancer. We aimed to investigate the association of HULC tagSNPs with the risk and prognosis of hepatocellular cancer, as well as… read more here.
Keywords: risk; hulc; hcc risk; lncrna hulc ... See more keywords
Long non-coding RNA highly up-regulated in liver cancer protects tumor necrosis factor-alpha-induced inflammatory injury by down-regulation of microRNA-101 in ATDC5 cells.
Sign Up to like & getrecommendations! Published in 2019 at "International immunopharmacology"
DOI: 10.1016/j.intimp.2019.04.004
Abstract: BACKGROUND Osteoarthritis (OA) is a familiar joint degenerative disease. Long non-coding RNAs (lncRNAs) play vital roles in the pathogenesis of OA. Nevertheless, the regulatory impacts of lncRNA highly up-regulated in liver cancer (lncRNA-HULC) on OA… read more here.
Keywords: hulc; mir 101; inflammatory injury; atdc5 cells ... See more keywords
β-Elemene suppresses tumor growth of diffuse large B-cell lymphoma through regulating lncRNA HULC-mediated apoptotic pathway
Sign Up to like & getrecommendations! Published in 2020 at "Bioscience Reports"
DOI: 10.1042/bsr20190804
Abstract: Abstract Background: Diffuse large B-cell lymphoma (DLBCL) is considered the most common aggressive subtype of lymphoma. A number of DLBCL patients fail to achieve a response to currently available therapies or develop resistance. β-Elemene is… read more here.
Keywords: dlbcl; hulc; diffuse large; lymphoma ... See more keywords
LPS promotes the progression of sepsis by activation of lncRNA HULC/miR-204-5p/TRPM7 network in HUVECs
Sign Up to like & getrecommendations! Published in 2020 at "Bioscience Reports"
DOI: 10.1042/bsr20200740
Abstract: Abstract Sepsis is a systemic inflammatory response syndrome caused by infection. Lipopolysaccharide (LPS) has been reported to induce inflammatory responses, and long non-coding RNA highly up-regulated in liver cancer (HULC) expression was associated with the… read more here.
Keywords: mir 204; sepsis; hulc; trpm7 ... See more keywords
Selective loading of exosomal HULC and miR-372 is responsible for chondrocyte death during OA pathogenesis
Sign Up to like & getrecommendations! Published in 2017 at "Animal Cells and Systems"
DOI: 10.1080/19768354.2017.1406871
Abstract: ABSTRACT Exosomes are membranous vesicles containing various biomolecules, including non-coding RNAs (ncRNAs). ncRNAs are secreted from several cell types and are involved in various biological functions, including cellular communication. The aim of this study was… read more here.
Keywords: chondrocyte death; death; hulc; pathogenesis ... See more keywords
AlncRNA HULC as an effective biomarker for surveillance of the outcome of cancer: A meta-analysis
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DOI: 10.1371/journal.pone.0171210
Abstract: Purpose High expression of highly upregulated in iver cancer (HULC) has been found associated with increased metastasis and poor prognosis with cancer. This meta-analysis aimed to determine the pooled effect of HULC on metastasis and… read more here.
Keywords: hulc; cancer meta; metastasis; cancer ... See more keywords
Long noncoding RNA HULC contributes to paclitaxel resistance in ovarian cancer via miR-137/ITGB8 axis
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DOI: 10.1515/biol-2021-0058
Abstract: Abstract Long noncoding RNA (lncRNA) highly upregulated in liver cancer (HULC) has been reported to be implicated in chemoresistance. However, the potential mechanism of HULC in paclitaxel (PTX)-resistant ovarian cancer (OC) remains undefined. The expression… read more here.
Keywords: long noncoding; mir 137; hulc; ptx ... See more keywords
LncRNA HULC promotes non-small cell lung cancer cell proliferation and inhibits the apoptosis by up-regulating sphingosine kinase 1 (SPHK1) and its downstream PI3K/Akt pathway.
Sign Up to like & getrecommendations! Published in 2018 at "European review for medical and pharmacological sciences"
DOI: 10.26355/eurrev_201812_16637
Abstract: OBJECTIVE LncRNA HULC has been proved to have important functions in the pathogenesis of several types of cancers. While its involvement in non-small cell lung cancer (NSCLC), which is one of the most common malignancies,… read more here.
Keywords: hulc; hulc overexpression; cell proliferation; sphk1 ... See more keywords