Omentin‐regulated proteins combine a pro‐inflammatory phenotype with an anti‐inflammatory counterregulation in human adipocytes: A proteomics analysis
Sign Up to like & getrecommendations! Published in 2019 at "Diabetes/Metabolism Research and Reviews"
DOI: 10.1002/dmrr.3074
Abstract: Experimental and epidemiological studies reported controversial data on the role of omentin in type 2 diabetes and cardiovascular diseases. This study aimed to characterise the impact of omentin on the secretome of human adipocytes to… read more here.
Keywords: combine pro; omentin regulated; regulated proteins; proteins combine ... See more keywords
Fucoxanthin and Its Metabolite Fucoxanthinol Do Not Induce Browning in Human Adipocytes.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.7b03931
Abstract: Rodent studies suggest that the antiobesity effects of fucoxanthin relate to activation of brown fat and conversion of white adipocytes to the brown phenotype. To evaluate the browning effect in human adipocytes, we investigated the genes… read more here.
Keywords: adipocytes fucoxanthin; metabolite fucoxanthinol; fucoxanthinol induce; human adipocytes ... See more keywords
Small-Molecule Inhibitors Targeting Lipolysis in Human Adipocytes.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.1c10836
Abstract: Chronically elevated circulating fatty acid levels promote lipid accumulation in nonadipose tissues and cause lipotoxicity. Adipose triglyceride lipase (ATGL) critically determines the release of fatty acids from white adipose tissue, and accumulating evidence suggests that… read more here.
Keywords: small molecule; human adipocytes; inhibitor; lipolysis human ... See more keywords
Natriuretic peptides promote glucose uptake in a cGMP-dependent manner in human adipocytes
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-19619-0
Abstract: Robust associations between low plasma level of natriuretic peptides (NP) and increased risk of type 2 diabetes (T2D) have been recently reported in humans. Adipose tissue (AT) is a known target of NP. However it… read more here.
Keywords: glucose uptake; cgmp dependent; human adipocytes; dependent manner ... See more keywords
Towards better models for studying human adipocytes in vitro
Sign Up to like & getrecommendations! Published in 2022 at "Adipocyte"
DOI: 10.1080/21623945.2022.2104514
Abstract: ABSTRACT With obesity and its comorbidities continuing to rise, we urgently need to improve our understanding of what mechanisms trigger the white adipose tissue to become dysfunctional in response to over-feeding. The recent invent of… read more here.
Keywords: adipocytes vitro; models studying; better models; human adipocytes ... See more keywords
Phenolic compounds apigenin, hesperidin and kaempferol reduce in vitro lipid accumulation in human adipocytes
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Translational Medicine"
DOI: 10.1186/s12967-017-1343-0
Abstract: BackgroundAdipocytes derived from human mesenchymal stem cells (MSCs) are widely used to investigate adipogenesis. Taking into account both the novelty of these MSCs and the scarcity of studies focused on the effects of phenolic compounds,… read more here.
Keywords: accumulation; kaempferol; apigenin hesperidin; hesperidin ... See more keywords
Maresin 1 Exerts a Tissue-Specific Regulation of Adipo-Hepato-Myokines in Diet-Induced Obese Mice and Modulates Adipokine Expression in Cultured Human Adipocytes in Basal and Inflammatory Conditions
Sign Up to like & getrecommendations! Published in 2023 at "Biomolecules"
DOI: 10.3390/biom13060919
Abstract: This study analyses the effects of Maresin 1 (MaR1), a docosahexaenoic acid (DHA)-derived specialized proresolving lipid mediator with anti-inflammatory and insulin-sensitizing actions, on the expression of adipokines, including adiponectin, leptin, dipeptidyl peptidase 4 (DPP-4), cardiotrophin-1… read more here.
Keywords: human adipocytes; expression; induced obese; mice ... See more keywords
Multiple Direct Effects of the Dietary Protoalkaloid N-Methyltyramine in Human Adipocytes
Sign Up to like & getrecommendations! Published in 2022 at "Nutrients"
DOI: 10.3390/nu14153118
Abstract: Dietary amines have been the subject of a novel interest in nutrition since the discovery of trace amine-associated receptors (TAARs), especially TAAR-1, which recognizes tyramine, phenethylamine, tryptamine, octopamine, N-methyltyramine (NMT), synephrine, amphetamine and related derivatives.… read more here.
Keywords: glucose transport; methyltyramine; human adipocytes; direct effects ... See more keywords
Opipramol Inhibits Lipolysis in Human Adipocytes without Altering Glucose Uptake and Differently from Antipsychotic and Antidepressant Drugs with Adverse Effects on Body Weight Control
Sign Up to like & getrecommendations! Published in 2020 at "Pharmaceuticals"
DOI: 10.3390/ph13030041
Abstract: Treatment with several antipsychotic drugs exhibits a tendency to induce weight gain and diabetic complications. The proposed mechanisms by which the atypical antipsychotic drug olanzapine increases body weight include central dysregulations leading to hyperphagia and… read more here.
Keywords: human adipocytes; lipolysis; opipramol inhibits; body weight ... See more keywords