DNA methylation is not involved in specific down-regulation of HSD3B2, NR4A1 and RARB genes in androgen-secreting cells of human adrenal cortex
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DOI: 10.1016/j.mce.2016.09.024
Abstract: We hypothesized that DNA methylation is involved in human adrenal functional zonation. mRNAs expression and methylation pattern of RARB, NR4A1 and HSD3B2 genes in human adrenal tissues (HAT) and in pediatric virilizing adrenocortical tumors (VAT)… read more here.
Keywords: methylation; human adrenal; rarb; hsd3b2 ... See more keywords
The Human Adrenal Gland Proteome Defined by Transcriptomics and Antibody-Based Profiling
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DOI: 10.1210/en.2016-1758
Abstract: The adrenal gland is a composite endocrine organ with vital functions that include the synthesis and release of glucocorticoids and catecholamines. To define the molecular landscape that underlies the specific functions of the adrenal gland,… read more here.
Keywords: human adrenal; adrenal gland; gland proteome; expression ... See more keywords
Ectopic localization of CYP11B1 and CYP11B2-expressing cells in the normal human adrenal gland
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DOI: 10.1371/journal.pone.0279682
Abstract: The sharp line of demarcation between zona glomerulosa (ZG) and zona fasciculata (ZF) has been recently challenged suggesting that this interface is no longer a compartment boundary. We have used immunohistochemical analyses to study the… read more here.
Keywords: cyp11b1; expressing cells; cyp11b2; human adrenal ... See more keywords