Integrative single-cell analysis of transcriptional and epigenetic states in the human adult brain
Sign Up to like & getrecommendations! Published in 2018 at "Nature biotechnology"
DOI: 10.1038/nbt.4038
Abstract: Detailed characterization of the cell types in the human brain requires scalable experimental approaches to examine multiple aspects of the molecular state of individual cells, as well as computational integration of the data to produce… read more here.
Keywords: single cell; brain integrative; human adult; brain ... See more keywords
Hyperoxia Induces Inflammation and Cytotoxicity in Human Adult Cardiac Myocytes
Sign Up to like & getrecommendations! Published in 2017 at "SHOCK"
DOI: 10.1097/shk.0000000000000740
Abstract: ABSTRACT Supplemental oxygen (O2) is used as adjunct therapy in anesthesia, emergency, and intensive care medicine. We hypothesized that excessive O2 levels (hyperoxia) can directly injure human adult cardiac myocytes (HACMs). HACMs obtained from the… read more here.
Keywords: cardiac myocytes; adult cardiac; hyperoxia; human adult ... See more keywords
Response to: Comment on ‘Human adult neurogenesis across the ages: An immunohistochemical study’
Sign Up to like & getrecommendations! Published in 2017 at "Neuropathology and Applied Neurobiology"
DOI: 10.1111/nan.12394
Abstract: Dear Editor, It is with great interest that we read the comment by Marucci [1] referring to our publication ‘Human adult neurogenesis across the ages: An immunohistochemical study’ [2]. Since the seminal paper of Eriksson… read more here.
Keywords: neurogenesis; study; human adult; neurogenesis across ... See more keywords
Comparing Circadian Dynamics in Primary Derived Stem Cells from Different Sources of Human Adult Tissue
Sign Up to like & getrecommendations! Published in 2017 at "Stem Cells International"
DOI: 10.1155/2017/2057168
Abstract: Optimising cell/tissue constructs so that they can be successfully accepted and integrated within a host body is essential in modern tissue engineering. To do this, adult stem cells are frequently utilised, but there are many… read more here.
Keywords: tissue; derived stem; human adult; stem ... See more keywords
Mechanistic Insights Into MicroRNA-Induced Neuronal Reprogramming of Human Adult Fibroblasts
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Neuroscience"
DOI: 10.3389/fnins.2018.00522
Abstract: The use of transcriptional factors as cell fate regulators are often the primary focus in the direct reprogramming of somatic cells into neurons. However, in human adult fibroblasts, deriving functionally mature neurons with high efficiency… read more here.
Keywords: adult fibroblasts; human adult; transcription factors; insights microrna ... See more keywords
Human Adult Astrocyte Extracellular Vesicle Transcriptomics Study Identifies Specific RNAs Which Are Preferentially Secreted as EV Luminal Cargo
Sign Up to like & getrecommendations! Published in 2023 at "Genes"
DOI: 10.3390/genes14040853
Abstract: Astrocytes are central nervous system (CNS)-restricted glial cells involved in synaptic function and CNS blood flow regulation. Astrocyte extracellular vesicles (EVs) participate in neuronal regulation. EVs carry RNAs, either surface-bound or luminal, which can be… read more here.
Keywords: cargo; adult astrocyte; adult; human adult ... See more keywords
Enhanced Anti-Cancer Effects of Conditioned Medium from Hypoxic Human Adult Dermal Fibroblasts on Cervical Cancer Cells
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23095134
Abstract: Hypoxia regulates fibroblast function by changing intracellular signaling and secretion factors, that influence the states of nearby cells. In this work, we investigated how medium (CM) from human adult dermal fibroblasts (HDFs) cultured in normoxic… read more here.
Keywords: cervical cancer; anti cancer; human adult; cancer effects ... See more keywords
Evaluating the Effect of Hypoxia on Human Adult Mesenchymal Stromal Cell Chondrogenesis In Vitro: A Systematic Review
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms232315210
Abstract: Human adult mesenchymal stromal cells (MSCs) from a variety of sources may be used to repair defects in articular cartilage by inducing them into chondrogenic differentiation. The conditions in which optimal chondrogenic differentiation takes place… read more here.
Keywords: effect; adult mesenchymal; human adult; hypoxia ... See more keywords
Human adult pluripotency: Facts and questions
Sign Up to like & getrecommendations! Published in 2019 at "World Journal of Stem Cells"
DOI: 10.4252/wjsc.v11.i1.1
Abstract: Cellular reprogramming and induced pluripotent stem cell (IPSC) technology demonstrated the plasticity of adult cell fate, opening a new era of cellular modelling and introducing a versatile therapeutic tool for regenerative medicine. While IPSCs are… read more here.
Keywords: adult; pluripotency; human adult; pluripotent stem ... See more keywords