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Published in 2017 at "Acta tropica"
DOI: 10.1016/j.actatropica.2016.05.009
Abstract: INTRODUCTION Sleeping sickness or Human African Trypanosomiasis (HAT) is a neglected tropical disease of public health importance across much of Sub-Saharan Africa. In Uganda, chronic T. b. gambiense HAT (gHAT) and acute T. b. rhodesiense…
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Keywords:
trypanosomiasis;
staff;
surveillance;
human african ... See more keywords
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Published in 2021 at "Indian journal of medical microbiology"
DOI: 10.1016/j.ijmmb.2021.06.012
Abstract: A young female patient from Ahmedabad city presented with acute febrile illness and bicytopenia (leukopenia and thrombocytopenia). She returned to India after recent visit to East Africa. Human African Trypanosomiasis (Sleeping sickness) was diagnosed by…
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Keywords:
trypanosomiasis rare;
human african;
case;
african trypanosomiasis ... See more keywords
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Published in 2017 at "Nature Microbiology"
DOI: 10.1038/s41564-017-0085-3
Abstract: Only two trypanosome subspecies are able to cause human African trypanosomiasis. To establish an infection in human blood, they must overcome the innate immune system by resisting the toxic effects of trypanolytic factor 1 and…
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Keywords:
associated protein;
human african;
serum resistance;
resistance associated ... See more keywords
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Published in 2022 at "Journal of Medical Entomology"
DOI: 10.1093/jme/tjab225
Abstract: Abstract Human African trypanosomiasis (HAT), despite considerable progress in the control, is still occurring in many countries in both west and central African regions. The HAT situation in the Republic of Congo has always been…
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Keywords:
human african;
african trypanosomiasis;
situation;
republic congo ... See more keywords
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Published in 2022 at "Current Opinion in Infectious Diseases"
DOI: 10.1097/qco.0000000000000860
Abstract: Purpose of review Gambiense human African trypanosomiasis (gHAT), a disease that has killed hundreds of thousands as recently as the 1990s, could be on the verge of elimination or even eradication. This review describes recent…
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Keywords:
gambiense human;
african trypanosomiasis;
elimination;
human african ... See more keywords
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Published in 2022 at "PLOS Neglected Tropical Diseases"
DOI: 10.1101/2022.08.26.22279255
Abstract: Gambiense human African trypanosomiasis (gHAT) is a deadly vector-borne, neglected tropical disease found in West and Central Africa targeted for elimination of transmission (EoT) by 2030. The recent pandemic has illustrated how it can be…
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Keywords:
gambiense human;
african trypanosomiasis;
human african;
interruption ... See more keywords
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Published in 2018 at "Infectious Diseases of Poverty"
DOI: 10.1186/s40249-018-0472-x
Abstract: BackgroundThe recent development of rapid diagnostic tests (RDTs) for human African trypanosomiasis (HAT) enables elimination programmes to decentralise serological screening services to frontline health facilities. However, patients must still undertake multiple onwards referral steps to…
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Keywords:
microscopy;
rapid diagnostic;
human african;
rdt ... See more keywords
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Published in 2017 at "PLoS Neglected Tropical Diseases"
DOI: 10.1371/journal.pntd.0005833
Abstract: Background Human African trypanosomiasis (HAT), a lethal disease induced by Trypanosoma brucei gambiense, has a range of clinical outcomes in its human host in West Africa: an acute form progressing rapidly to second stage, spontaneous…
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Keywords:
ci95;
risk;
human african;
ci95 bonf ... See more keywords
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Published in 2018 at "PLoS Neglected Tropical Diseases"
DOI: 10.1371/journal.pntd.0006250
Abstract: Background The control or elimination of neglected tropical diseases (NTDs) has targets defined by the WHO for 2020, reinforced by the 2012 London Declaration. We estimated the economic impact to individuals of meeting these targets…
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Keywords:
human african;
tropical diseases;
disease;
african trypanosomiasis ... See more keywords
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Published in 2020 at "PLoS Neglected Tropical Diseases"
DOI: 10.1371/journal.pntd.0007737
Abstract: Background Large-scale control of sleeping sickness has led to a decline in the number of cases of Gambian human African trypanosomiasis (g-HAT) to
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Keywords:
cattle pigs;
human african;
pigs tsetse;
brucei ... See more keywords
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Published in 2020 at "PLoS Neglected Tropical Diseases"
DOI: 10.1371/journal.pntd.0008270
Abstract: Over the past 20 years there has been a >95% reduction in the number of Gambian Human African trypanosomiasis (g-HAT) cases reported globally, largely as a result of large-scale active screening and treatment programmes. There…
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Keywords:
intervention;
tiny targets;
impact tiny;
human african ... See more keywords