Impact of sample processing on human airways microbial metagenomes.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of biotechnology"
DOI: 10.1016/j.jbiotec.2017.01.001
Abstract: Whole metagenome shotgun sequencing provides information about the gene content and the composition of microbial communities provided that the processing of the samples does not introduce a methodology-driven bias. We tested the impact of DNA… read more here.
Keywords: human airways; dna; sample processing; airways microbial ... See more keywords
Studies on citrullinated LL-37: detection in human airways, antibacterial effects and biophysical properties
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DOI: 10.1038/s41598-020-59071-7
Abstract: Arginine residues of the antimicrobial peptide LL-37 can be citrullinated by peptidyl arginine deiminases, which reduce the positive charge of the peptide. Notably, citrullinated LL-37 has not yet been detected in human samples. In addition,… read more here.
Keywords: human airways; detection human; bal fluid; citrullinated detection ... See more keywords
Adaptation of Nontypeable Haemophilus influenzae in Human Airways in COPD: Genome Rearrangements and Modulation of Expression of HMW1 and HMW2
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DOI: 10.1128/mbio.00140-23
Abstract: Nontypeable Haemophilus influenzae (NTHi) persists in the lower airways of adults with chronic obstructive pulmonary disease (COPD) for months to years, increasing airway inflammation that accelerates the progressive loss of lung function. Understanding the mechanisms… read more here.
Keywords: human airways; persistence; copd; expression ... See more keywords
Smoking-associated increase in mucins 1 and 4 in human airways
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DOI: 10.1186/s12931-020-01498-7
Abstract: Smoking-related chronic obstructive pulmonary disease (COPD) is associated with dysregulated production of mucus. Mucins (MUC) are important both for mucus secretion and epithelial defense. We have examined the distribution of MUC1 and MUC4 in the… read more here.
Keywords: human airways; never smokers; soluble muc1; expression ... See more keywords