Substitutions at a rheostat position in human aldolase A cause a shift in the conformational population
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DOI: 10.1002/pro.4222
Abstract: Some protein positions play special roles in determining the magnitude of protein function: at such “rheostat” positions, varied amino acid substitutions give rise to a continuum of functional outcomes, from wild type (or enhanced), to… read more here.
Keywords: rheostat positions; human aldolase; substitutions rheostat; position human ... See more keywords