Isolation and Characterization of Human Alveolar Type II Cells.
Sign Up to like & getrecommendations! Published in 2018 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-8570-8_7
Abstract: Alveolar type II (ATII) cells synthesize, store, and secrete pulmonary surfactant and restore the epithelium after damage to the alveolar epithelium. Isolation of human ATII cells provides a valuable tool to study their function under… read more here.
Keywords: isolation characterization; characterization human; human alveolar; alveolar type ... See more keywords
Pilot investigation on the dose-dependent impact of irradiation on primary human alveolar osteoblasts in vitro
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-99323-8
Abstract: Radiotherapy of head and neck squamous cell carcinoma can lead to long-term complications like osteoradionecrosis, resulting in severe impairment of the jawbone. Current standard procedures require a 6-month wait after irradiation before dental reconstruction can… read more here.
Keywords: irradiation; impact; human alveolar; dose dependent ... See more keywords
Human alveolar macrophages predominately express combined classical M1 and M2 surface markers in steady state
Sign Up to like & getrecommendations! Published in 2018 at "Respiratory Research"
DOI: 10.1186/s12931-018-0777-0
Abstract: Alveolar macrophages (AM) are critical to the homeostasis of the inflammatory environment in the lung. Differential expression of surface markers classifies macrophages to either classically (M1) or alternatively activated (M2). We investigated the phenotype of… read more here.
Keywords: alveolar macrophages; human alveolar; surface markers; macrophages predominately ... See more keywords
AmpliSeq transcriptome analysis of human alveolar and monocyte-derived macrophages over time in response to Mycobacterium tuberculosis infection
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DOI: 10.1371/journal.pone.0198221
Abstract: Human alveolar macrophages (HAM) are primary bacterial niche and immune response cells during Mycobacterium tuberculosis (M.tb) infection, and human blood monocyte-derived macrophages (MDM) are a model for investigating M.tb-macrophage interactions. Here, we use a targeted… read more here.
Keywords: ham; response; infection; time ... See more keywords
Fabrication and Characterization of 3D Bioprinted Triple-layered Human Alveolar Lung Models
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DOI: 10.18063/ijb.v7i2.332
Abstract: The global prevalence of respiratory diseases caused by infectious pathogens has resulted in an increased demand for realistic in-vitro alveolar lung models to serve as suitable disease models. This demand has resulted in the fabrication… read more here.
Keywords: triple layered; human alveolar; fabrication; alveolar lung ... See more keywords
Positional integration of lung adenocarcinoma susceptibility loci with primary human alveolar epithelial cell epigenomes.
Sign Up to like & getrecommendations! Published in 2018 at "Epigenomics"
DOI: 10.2217/epi-2018-0003
Abstract: AIM To identify functional lung adenocarcinoma (LUAD) risk SNPs. MATERIALS & METHODS Eighteen validated LUAD risk SNPs (p ≤ 5 × 10-8) and 930 SNPs in high linkage disequilibrium (r2 > 0.5) were integrated with epigenomic information from primary human alveolar… read more here.
Keywords: lung adenocarcinoma; luad risk; human alveolar; risk snps ... See more keywords
Human alveolar macrophage metabolism is compromised during Mycobacterium tuberculosis infection
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.1044592
Abstract: Pulmonary macrophages have two distinct ontogenies: long-lived embryonically-seeded alveolar macrophages (AM) and bone marrow-derived macrophages (BMDM). Here, we show that after infection with a virulent strain of Mycobacterium tuberculosis (H37Rv), primary murine AM exhibit a… read more here.
Keywords: mycobacterium tuberculosis; human alveolar; infection; macrophage metabolism ... See more keywords
Expression and Function of ABC Transporters in Human Alveolar Epithelial Cells
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DOI: 10.3390/biom12091260
Abstract: ATP-binding cassette (ABC) transporters are a large superfamily of membrane transporters that facilitate the translocation of different substrates. While ABC transporters are clearly expressed in various tumor cells where they can play a role in… read more here.
Keywords: abc transporters; human alveolar; alveolar epithelial; epithelial cells ... See more keywords
Unveiling the Toxicity of Fine and Nano-Sized Airborne Particles Generated from Industrial Thermal Spraying Processes in Human Alveolar Epithelial Cells
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23084278
Abstract: High-energy industrial processes have been associated with particle release into workplace air that can adversely affect workers’ health. The present study assessed the toxicity of incidental fine (PGFP) and nanoparticles (PGNP) emitted from atmospheric plasma… read more here.
Keywords: thermal spraying; alveolar epithelial; toxicity; human alveolar ... See more keywords
Notoginsenoside R1 promotes differentiation of human alveolar osteoblasts in inflammatory microenvironment through inhibiting NF-κB pathway and activating Wnt/β-catenin pathway
Sign Up to like & getrecommendations! Published in 2020 at "Molecular Medicine Reports"
DOI: 10.3892/mmr.2020.11537
Abstract: Alveolar bone is vital for dental implantation and periodontal treatment. Notoginsenoside R1 (NTR1) may promote the differentiation of human alveolar osteoblasts (HAOBs), but the underlying molecular mechanisms remain unclear. The present study investigated the pro-differentiation… read more here.
Keywords: catenin; human alveolar; differentiation human; pathway ... See more keywords