Combination of paromomycin plus human anti-TNF-α antibodies to control the local inflammatory response in BALB/ mice with cutaneous leishmaniasis lesions.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of dermatological science"
DOI: 10.1016/j.jdermsci.2018.07.005
Abstract: BACKGROUND Cutaneous leishmaniasis (CL) skin lesions are the result of a deregulated immune response, which is unable to eliminate Leishmania parasites. The control of both, parasites and host immune response, is critical to prevent tissue… read more here.
Keywords: combination; tnf; response; inflammatory ... See more keywords
Augmenting Vaccine Immunogenicity through the Use of Natural Human Anti-rhamnose Antibodies
Sign Up to like & getrecommendations! Published in 2018 at "ACS Chemical Biology"
DOI: 10.1021/acschembio.8b00312
Abstract: Utilizing natural antibodies to augment vaccine immunogenicity is a promising approach toward cancer immunotherapy. Anti-rhamnose (anti-Rha) antibodies are some of the most common natural anti-carbohydrate antibodies present in human serum. Therefore, rhamnose can be utilized… read more here.
Keywords: human anti; rha; vaccine; rha antibodies ... See more keywords
Passive immunisation of convalescent human anti-Zika plasma protects against challenge with New World Zika virus in cynomolgus macaques
Sign Up to like & getrecommendations! Published in 2020 at "NPJ Vaccines"
DOI: 10.1038/s41541-020-00234-y
Abstract: Zika virus (ZIKV) causes neurological complications in susceptible individuals, highlighted in the recent South American epidemic. Natural ZIKV infection elicits host responses capable of preventing subsequent re-infection, raising expectations for effective vaccination. Defining protective immune… read more here.
Keywords: challenge; convalescent; anti; zikv ... See more keywords
Human anti-thrombospondin type 1 domain-containing 7A antibodies induce membranous nephropathy through activation of lectin complement pathway
Sign Up to like & getrecommendations! Published in 2018 at "Bioscience Reports"
DOI: 10.1042/bsr20180131
Abstract: To investigate whether the human anti-thrombospondin type 1 domain-containing 7A (THSD7A) antibody-induced membranous nephropathy (MN) is mediated by activating lectin complement pathway. Automatic biochemical apparatus was used to assess renal function of mice. The serum… read more here.
Keywords: complement pathway; lectin complement; thsd7a; human anti ... See more keywords
New phytochemicals as potential human anti-aging compounds: Reality, promise, and challenges
Sign Up to like & getrecommendations! Published in 2018 at "Critical Reviews in Food Science and Nutrition"
DOI: 10.1080/10408398.2016.1233860
Abstract: ABSTRACT Aging is an inevitable process influenced by genetic, lifestyle, and environmental factors. Indirect evidence shows that several phytochemicals can have anti-aging capabilities, although direct evidence in this field is still limited. This report aims… read more here.
Keywords: phytochemicals potential; potential human; new phytochemicals; human anti ... See more keywords
Human anti‐α‐fucose antibodies are xenoreactive toward GGTA1/CMAH knockout pigs
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DOI: 10.1111/xen.12629
Abstract: Progress has been made in overcoming antibody‐mediated rejection of porcine xenografts by deleting pig genes that produce unique carbohydrate epitopes. Pigs deficient in galactose α‐1,3 galactose (gene modified: GGTA1) and neu5Gc (gene modified: CMAH) have… read more here.
Keywords: antibody; anti fucose; human anti; ggta1 cmah ... See more keywords
Abstract 5629: Preclinical characterization of Sym023 a human anti-TIM3 antibody with a novel mechanism of action
Sign Up to like & getrecommendations! Published in 2018 at "Cancer Research"
DOI: 10.1158/1538-7445.am2018-5629
Abstract: Immunotherapy has become a major focus of research in oncology and blockade of immune checkpoints such as cytotoxic T-Lymphocyte Associated Protein 4 (CTLA4) and programmed cell death protein 1 (PD1) has been some of the… read more here.
Keywords: sym023 human; tim3 antibody; anti tim3; tim3 ... See more keywords
Profile of human anti-rabies treatment in the 'agreste' region of Pernambuco State, Brazil, 2010-2012.
Sign Up to like & getrecommendations! Published in 2017 at "Epidemiologia e servicos de saude : revista do Sistema Unico de Saude do Brasil"
DOI: 10.5123/s1679-49742017000100017
Abstract: Objective to describe the characteristics of reported human anti-rabies treatment in municipalities of the 'agreste' region of Pernambuco State, Brazil, 2010-2012. Methods this was a descriptive study using data from human anti-rabies medical records filed… read more here.
Keywords: region pernambuco; anti rabies; human anti; agreste region ... See more keywords