Cryptides Identified in Human Apolipoprotein B as New Weapons to Fight Antibiotic Resistance in Cystic Fibrosis Disease
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DOI: 10.3390/ijms21062049
Abstract: Chronic respiratory infections are the main cause of morbidity and mortality in cystic fibrosis (CF) patients, and are characterized by the development of multidrug resistance (MDR) phenotype and biofilm formation, generally recalcitrant to treatment with… read more here.
Keywords: cystic fibrosis; microscopy; resistance; human apolipoprotein ... See more keywords
Impact of a Single Point Mutation on the Antimicrobial and Fibrillogenic Properties of Cryptides from Human Apolipoprotein B
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DOI: 10.3390/ph14070631
Abstract: Host defense peptides (HDPs) are gaining increasing interest, since they are endowed with multiple activities, are often effective on multidrug resistant bacteria and do not generally lead to the development of resistance phenotypes. Cryptic HDPs… read more here.
Keywords: point mutation; impact single; single point; human apolipoprotein ... See more keywords