“Precision on Two Wheels”Structural Refinement of 64Cu- and 68Ga-Labeled Bicyclic Peptides Targeting Nectin‑4 for Improved Tumor Imaging: From Preclinical Development to First-in-Human Application
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Medicinal Chemistry"
DOI: 10.1021/acs.jmedchem.5c02371
Abstract: The cell adhesion protein nectin-4 emerged as a valid therapeutic target for antibody- and peptide-drug conjugates in cancer. To support patient stratification for such targeted therapies, there is a clinical need for molecular imaging agents… read more here.
Keywords: 64cu 68ga; human application; 68ga labeled; tumor ... See more keywords
First human application of a flexible 3‐D endoscope for gastrointestinal endoscopic submucosal dissection
Sign Up to like & getrecommendations! Published in 2019 at "Digestive Endoscopy"
DOI: 10.1111/den.13374
Abstract: Over decades ago, rigid laparoscopy instrumented with 3-dimmentional (3D) view was introduced in minimally invasive surgery. Since then, there has been an advancement in the stereoscopic technology with implement of higher resolution and illumination1,2 .… read more here.
Keywords: gastrointestinal endoscopic; endoscope gastrointestinal; human application; application flexible ... See more keywords