Structure of Human ATG9A, the Only Transmembrane Protein of the Core Autophagy Machinery.
Sign Up to like & getrecommendations! Published in 2020 at "Cell reports"
DOI: 10.1016/j.celrep.2020.107837
Abstract: Autophagy is a catabolic process involving capture of cytoplasmic materials into double-membraned autophagosomes that subsequently fuse with lysosomes for degradation of the materials by lysosomal hydrolases. One of the least understood components of the autophagy… read more here.
Keywords: autophagy machinery; structure; structure human; human atg9a ... See more keywords
The structure of human ATG9A and its interplay with the lipid bilayer
Sign Up to like & getrecommendations! Published in 2020 at "Autophagy"
DOI: 10.1080/15548627.2020.1830522
Abstract: ABSTRACT ATG9, the only transmembrane protein in the core macroautophagy/autophagy machinery, is a key player in the early stages of autophagosome formation. Yet, the lack of a high-resolution structure of ATG9 was a major impediment… read more here.
Keywords: structure; atg9a interplay; bilayer; human atg9a ... See more keywords