Structure of the human ATM kinase and mechanism of Nbs1 binding
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DOI: 10.7554/elife.74218
Abstract: DNA double-strand breaks (DSBs) can lead to mutations, chromosomal rearrangements, genome instability, and cancer. Central to the sensing of DSBs is the ATM (Ataxia-telangiectasia mutated) kinase, which belongs to the phosphatidylinositol 3-kinase-related protein kinase (PIKK)… read more here.
Keywords: kinase; atm kinase; human atm; atm ... See more keywords