Genetics of human autoimmunity: From genetic information to functional insights.
Sign Up to like & getrecommendations! Published in 2018 at "Clinical immunology"
DOI: 10.1016/j.clim.2017.08.017
Abstract: Genome-wide association studies have identified hundreds of risk variants associated with human autoimmune diseases. Recent evidence suggests that a substantial portion of them affect gene expression in specific cell types. To obtain the functional insights… read more here.
Keywords: human autoimmunity; genetics human; genetics; functional insights ... See more keywords
Functional SNPs in the Human Autoimmunity-Associated Locus 17q12-21
Sign Up to like & getrecommendations! Published in 2019 at "Genes"
DOI: 10.3390/genes10020077
Abstract: Genome-wide association studies (GWASes) revealed several single-nucleotide polymorphisms (SNPs) in the human 17q12-21 locus associated with autoimmune diseases. However, follow-up studies are still needed to identify causative SNPs directly mediating autoimmune risk in the locus.… read more here.
Keywords: snps; human autoimmunity; functional snps; autoimmunity associated ... See more keywords