Synthesis, antibacterial, and antibiofilm potential of human autophagy 16 polypeptide and analogues
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DOI: 10.1002/pep2.24076
Abstract: This work demonstrates that the human autophagy 16 polypeptide (Atg16) has antibacterial and antibiofilm potential, perturbs both Gram positive and negative bacterial membranes and subsequently also produces ROS in compromised bacteria. Engineered Atg 16 analogues… read more here.
Keywords: autophagy polypeptide; antibacterial antibiofilm; antibiofilm potential; human autophagy ... See more keywords
Quantitation of Cardiolipin Binding to Human Autophagy (Mitophagy)-Related Atg-8 Proteins
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DOI: 10.1016/j.bpj.2016.11.2136
Abstract: The phospholipid cardiolipin (CL) has been proposed to play a role in selective mitochondrial autophagy, or mitophagy. CL externalization to the outer mitochondrial membrane would act as a signal for the human Atg8 ortholog subfamily,… read more here.
Keywords: cardiolipin binding; quantitation cardiolipin; cardiolipin; autophagy mitophagy ... See more keywords