Methylseleninic acid induces apoptosis of human bladder cancer cells through the ROS-mediated mitochondrial pathway.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of biochemical and molecular toxicology"
DOI: 10.1002/jbt.23387
Abstract: As the most common selenium derivative, methylseleninic acid (MSA) has attracted wide attention. Its apoptotic induction ability and the possible molecular mechanism in human bladder cancer (BC) J82 and T24 cells were investigated in the… read more here.
Keywords: apoptosis; t24 cells; methylseleninic acid; human bladder ... See more keywords
β‐Adrenoceptor signaling regulates proliferation and contraction of human bladder smooth muscle cells under pathological hydrostatic pressure
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.29056
Abstract: Partial bladder outlet obstruction (PBOO) promotes bladder detrusor hyperplasia, increases bladder pressure, and decreases bladder compliance. To extensively explore its underlying mechanism, our study aimed to investigate the effect of pathological hydrostatic pressure on human… read more here.
Keywords: pathological hydrostatic; human bladder; bladder; bladder smooth ... See more keywords
β‐Adrenoceptor regulates contraction and inflammatory cytokine expression of human bladder smooth muscle cells via autophagy under pathological hydrostatic pressure
Sign Up to like & getrecommendations! Published in 2020 at "Neurourology and Urodynamics"
DOI: 10.1002/nau.24517
Abstract: Abnormal intravesical pressure created by partial bladder outlet obstruction (PBOO) triggered the progression from chronic inflammation to fibrosis, initiating structural and functional alterations of bladder. To elucidate the underlying mechanisms of contraction and inflammatory response,… read more here.
Keywords: human bladder; bladder; contraction inflammatory; smooth muscle ... See more keywords
Copper(II) complexes with N′-methylsarcosinamide selective for human bladder cancer cells
Sign Up to like & getrecommendations! Published in 2019 at "Inorganica Chimica Acta"
DOI: 10.1016/j.ica.2019.01.013
Abstract: Abstract Two copper(II) complexes, [CuCl2(SarMeam)2] · H2O (1) and [Cu(NO3)2(SarMeam)2] (2) were obtained by reactions of N′-methylsarcosinamide (SarMeam) with copper(II) chloride and copper(II) nitrate in aqueous solutions. The complexes were characterized by X-ray crystallography, IR and UV-Vis… read more here.
Keywords: bladder cancer; copper; h2o; sarmeam ... See more keywords
Targeted and Untargeted Detection of DNA Adducts of Aromatic Amine Carcinogens in Human Bladder by Ultra-Performance Liquid Chromatography-High-Resolution Mass Spectrometry.
Sign Up to like & getrecommendations! Published in 2018 at "Chemical research in toxicology"
DOI: 10.1021/acs.chemrestox.8b00268
Abstract: Epidemiological studies have linked aromatic amines (AAs) from tobacco smoke and some occupational exposures with bladder cancer risk. Several epidemiological studies have also reported a plausible role for structurally related heterocyclic aromatic amines present in… read more here.
Keywords: human bladder; adduct; bladder; tobacco smoke ... See more keywords
Optimized Measurement Parameters of Sensory Evoked Cortical Potentials to Assess Human Bladder Afferents - A Randomized Study
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-54614-z
Abstract: Overactive bladder and voiding dysfunction are highly prevalent and often associated with malfunction of the bladder afferent pathways. Appropriate diagnostic tools for an objective assessment of afferent nerve function of the human bladder are currently… read more here.
Keywords: human bladder; randomized study; stimulation; bladder ... See more keywords
Apoptotic and anti-angiogenic effects of propolis against human bladder cancer: molecular docking and in vitro screening
Sign Up to like & getrecommendations! Published in 2021 at "Biomarkers"
DOI: 10.1080/1354750x.2021.2020903
Abstract: Abstract Introduction Bladder cancer is still of unknown initiation and progression, it is difficult to treat the patient once bladder cancer have a distant metastasis. Materials and methods In the present study, propolis extract was… read more here.
Keywords: bladder cancer; effects propolis; molecular docking; cancer ... See more keywords
Induction of apoptosis and autophagy by calcifying nanoparticles in human bladder cancer cells
Sign Up to like & getrecommendations! Published in 2017 at "Tumor Biology"
DOI: 10.1177/1010428317707688
Abstract: Calcifying nanoparticles have been linked to various types of human disease, but how they contribute to disease processes is unclear. Here, we examined whether and how calcifying nanoparticles isolated from patients with kidney stones are… read more here.
Keywords: bladder cancer; human bladder; apoptosis; microscopy ... See more keywords
Characterization of human bladder cancer patient-derived xenograft in vivo and in organoids.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2018.36.6_suppl.479
Abstract: 479Background: To establish and molecularly characterize a human bladder cancer patient-derived xenograft (PDX) in vivo and in an organoid system derived from the PDX for preclinical studies. Methods: Two-mm3 bits of urothelial carcinoma originated from… read more here.
Keywords: bladder cancer; human bladder; derived xenograft; cancer patient ... See more keywords
Casticin Induces DNA Damage and Impairs DNA Repair in Human Bladder Cancer TSGH-8301 Cells
Sign Up to like & getrecommendations! Published in 2019 at "AntiCancer Research"
DOI: 10.21873/anticanres.13291
Abstract: Background/Aim: Casticin shows anti-cancer effects in many types of cancer. However, there is no information regarding its role in DNA damage in human bladder cancer. The aim of this study was to investigate the effects… read more here.
Keywords: dna damage; human bladder; microscopy; casticin ... See more keywords
Functional Expression of Transient Receptor Potential and Piezo1 Channels in Cultured Interstitial Cells of Human-Bladder Lamina Propria
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2021.762847
Abstract: The interstitial cells in bladder lamina propria (LP-ICs) are believed to be involved in sensing/afferent signaling in bladder mucosa. Transient receptor potential (TRP) cation channels act as mechano- or chemo-sensors and may underlie some of… read more here.
Keywords: human bladder; trpa1; bladder; piezo1 ... See more keywords