Living with a large predator: Assessing the root causes of Human–brown bear conflict and their spatial patterns in Lahaul valley, Himachal Pradesh
Sign Up to like & getrecommendations! Published in 2022 at "Ecology and Evolution"
DOI: 10.1002/ece3.9120
Abstract: Abstract Brown bear‐mediated conflicts have caused immense economic loss to the local people living across the distribution range. In India, limited knowledge is available on the Himalayan brown bear (HBB), making human–brown bear conflict (HBC)… read more here.
Keywords: lahaul valley; bear conflict; brown bear; human brown ... See more keywords
Substantial Metabolic Activity of Human Brown Adipose Tissue during Warm Conditions and Cold-Induced Lipolysis of Local Triglycerides
Sign Up to like & getrecommendations! Published in 2018 at "Cell Metabolism"
DOI: 10.1016/j.cmet.2018.04.020
Abstract: Summary Current understanding of in vivo human brown adipose tissue (BAT) physiology is limited by a reliance on positron emission tomography (PET)/computed tomography (CT) scanning, which has measured exogenous glucose and fatty acid uptake but… read more here.
Keywords: bat; adipose tissue; human brown; warm conditions ... See more keywords
Human Brown Adipocyte Thermogenesis Is Driven by β2-AR Stimulation.
Sign Up to like & getrecommendations! Published in 2020 at "Cell metabolism"
DOI: 10.1016/j.cmet.2020.07.005
Abstract: Stimulation of brown adipose tissue (BAT) thermogenesis in humans has emerged as an attractive target to improve metabolic health. Pharmacological stimulations targeting the β3-adrenergic receptor (β3-AR), the adrenergic receptor believed to mediate BAT thermogenesis, have… read more here.
Keywords: brown adipocyte; stimulation; bat thermogenesis; adipocyte thermogenesis ... See more keywords
Angiotensin II participates in mitochondrial thermogenic functions via the activation of glycolysis in chemically induced human brown adipocytes
Sign Up to like & getrecommendations! Published in 2024 at "Scientific Reports"
DOI: 10.1038/s41598-024-61774-0
Abstract: Brown adipocytes are potential therapeutic targets for the prevention of obesity-associated metabolic diseases because they consume circulating glucose and fatty acids for heat production. Angiotensin II (Ang II) peptide is involved in the pathogenesis of… read more here.
Keywords: mitochondrial thermogenic; participates mitochondrial; human brown; thermogenic functions ... See more keywords
The effects of the β1‐adrenergic receptor antagonist bisoprolol administration on mirabegron‐stimulated human brown adipose tissue thermogenesis
Sign Up to like & getrecommendations! Published in 2024 at "Acta Physiologica"
DOI: 10.1111/apha.14127
Abstract: Pharmacological stimulation of human brown adipose tissue (BAT) has been hindered by ineffective activation or undesirable off‐target effects. Oral administration of the maximal allowable dose of mirabegron (200 mg), a β3‐adrenergic receptor (β3‐AR) agonist, has been… read more here.
Keywords: human brown; adrenergic receptor; adipose tissue; brown adipose ... See more keywords
Human brown adipose tissue: Classical brown rather than brite/beige?
Sign Up to like & getrecommendations! Published in 2020 at "Experimental Physiology"
DOI: 10.1113/ep087875
Abstract: What is the topic of this review? It has been suggested that human brown adipose tissue (BAT) is more similar to the brite/beige adipose tissue of mice than to classical BAT of mice. The basis… read more here.
Keywords: bat; brite beige; adipose tissue; tissue ... See more keywords
Deep learning enables the quantification of browning capacity of human adipose samples
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Big Data"
DOI: 10.1186/s40537-024-00879-9
Abstract: Background The recruitment of thermogenic adipocytes in human fat depots markedly improves metabolic disorders such as type 2 diabetes mellitus (T2DM). However, identification and quantification of thermogenic cells in human fats, especially in metabolic disorders… read more here.
Keywords: human adipose; brown like; signature genes; browning capacity ... See more keywords
Characterization of immortalized human brown and white pre-adipocyte cell models from a single donor
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DOI: 10.1371/journal.pone.0185624
Abstract: Brown adipose tissue with its constituent brown adipocytes is a promising therapeutic target in metabolic disorders due to its ability to dissipate energy and improve systemic insulin sensitivity and glucose homeostasis. The molecular control of… read more here.
Keywords: brown white; adipocyte; cell models; tert ... See more keywords