Interactions of human butyrylcholinesterase with phenylvalerate and acetylthiocholine as substrates and inhibitors: kinetic and molecular modeling approaches
Sign Up to like & getrecommendations! Published in 2019 at "Archives of Toxicology"
DOI: 10.1007/s00204-019-02423-8
Abstract: Phenyl valerate (PV) is a substrate for measuring the PVase activity of neuropathy target esterase (NTE), a key molecular event of organophosphorus-induced delayed neuropathy. A protein with PVase activity in chicken (model for delayed neurotoxicity)… read more here.
Keywords: human butyrylcholinesterase; butyrylcholinesterase; inhibition; site ... See more keywords
Butyrylcholinesterase, a stereospecific in vivo bioscavenger against nerve agent intoxication.
Sign Up to like & getrecommendations! Published in 2019 at "Biochemical pharmacology"
DOI: 10.1016/j.bcp.2019.113670
Abstract: Human butyrylcholinesterase (E.C. 3.1.1.8) purified from blood plasma has previously been shown to provide protection against up to five and a half times the median lethal dose of an organophosphorus nerve agent in several animal… read more here.
Keywords: agent; human butyrylcholinesterase; butyrylcholinesterase; median lethal ... See more keywords