Comparative analysis of genome-wide DNA methylation identifies patterns that associate with conserved transcriptional programs in osteosarcoma.
Sign Up to like & getrecommendations! Published in 2020 at "Bone"
DOI: 10.1016/j.bone.2020.115716
Abstract: Osteosarcoma is an aggressive tumor of the bone that primarily affects young adults and adolescents. Osteosarcoma is characterized by genomic chaos and heterogeneity. While inactivation of tumor protein p53 (TP53) is nearly universal other high… read more here.
Keywords: methylation; transcriptional programs; human canine; conserved transcriptional ... See more keywords
Proteases as prognostic markers in human and canine cancers
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DOI: 10.1111/vco.12223
Abstract: The extracellular matrix (ECM) is composed of several types of proteins, which interact and form dynamic networks. These components can modulate cell behaviour and actively influence the growth and differentiation of tissues. ECM is also… read more here.
Keywords: canine cancers; markers human; human canine; oncology ... See more keywords
Cannabidiol Induces Apoptosis and Perturbs Mitochondrial Function in Human and Canine Glioma Cells
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2021.725136
Abstract: Cannabidiol (CBD), the major non-psychoactive compound found in cannabis, is frequently used both as a nutraceutical and therapeutic. Despite anecdotal evidence as an anticancer agent, little is known about the effect CBD has on cancer… read more here.
Keywords: cbd; human canine; canine glioma; canine ... See more keywords
Ubiquitin-Specific Proteases as Potential Therapeutic Targets in Bladder Cancer—In Vitro Evaluation of Degrasyn and PR-619 Activity Using Human and Canine Models
Sign Up to like & getrecommendations! Published in 2023 at "Biomedicines"
DOI: 10.3390/biomedicines11030759
Abstract: Background: The inhibition of ubiquitin-specific proteases (USPs) is a novel and promising direction in the development of molecularly targeted therapies in oncology. The aim of the present study was to examine whether Degrasyn could be… read more here.
Keywords: vitro; cell; human canine; ubiquitin specific ... See more keywords
A Comparative in Silico Analysis of CD24’s Prognostic Value in Human and Canine Prostate Cancer
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DOI: 10.3390/jpm11030232
Abstract: CD24 is a cell surface molecule anchored by glycosyl-phosphatidyl-inositol and expressed by different human cancers, including prostate cancer (PC). Some studies have demonstrated that CD24 expression is associated with poor patient outcome; however, few studies… read more here.
Keywords: human canine; canine; silico analysis; prostate cancer ... See more keywords
Autochthonous Human and Canine Strongyloides stercoralis Infection in Europe: Report of a Human Case in An Italian Teen and Systematic Review of the Literature
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DOI: 10.3390/pathogens9060439
Abstract: Autochthonous human and canine strongyloidiasis is reported in Europe but is unclear whether the transmission of infection still occurs. We report a previously unpublished human case in an Italian teen and perform a systematic review… read more here.
Keywords: strongyloidiasis; human canine; case; human case ... See more keywords
Doxorubicin-Loaded Lipid Nanoparticles Coated with Calcium Phosphate as a Potential Tool in Human and Canine Osteosarcoma Therapy
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics14071362
Abstract: Osteosarcoma (OSA) is the most frequently diagnosed primary malignant bone tumor in humans and dogs. In both species, standard chemotherapy can be limited by multidrug resistance of neoplastic cells, which prevents intracellular accumulation of cytotoxic… read more here.
Keywords: calcium phosphate; human canine; osteosarcoma; coated calcium ... See more keywords
The influence of Mycoplasma species on human and canine semen quality: a review
Sign Up to like & getrecommendations! Published in 2022 at "Asian Journal of Andrology"
DOI: 10.4103/aja2021124
Abstract: Mycoplasma species (spp.) are bacteria that are difficult to detect. Currently, the polymerase chain reaction (PCR) is considered the most effective diagnostic tool to detect these microorganisms in both human and veterinary medicine. There are… read more here.
Keywords: mycoplasma; species human; human canine; canine mycoplasma ... See more keywords
Comparative histopathology and immunohistochemistry of human and canine mammary tumors
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DOI: 10.4314/ovj.v8i3.3
Abstract: This study aimed at establishing aspects of comparison between canine and human mammary gland tumors. In order to achieve that, 44 specimens of canine mammary tumors and 70 specimens of human breast tumors were examined… read more here.
Keywords: canine mammary; mammary tumors; human canine; histopathology ... See more keywords