Quantitative susceptibility mapping of the human carotid artery: Assessing sensitivity to elastin and collagen ex vivo
Sign Up to like & getrecommendations! Published in 2025 at "Magnetic Resonance in Medicine"
DOI: 10.1002/mrm.30500
Abstract: The aim is to establish the relationship between carotid susceptibility and microstructural components in diseased carotid arteries. read more here.
Keywords: susceptibility; carotid artery; susceptibility mapping; human carotid ... See more keywords
Dual roles of heparanase in human carotid plaque calcification.
Sign Up to like & getrecommendations! Published in 2019 at "Atherosclerosis"
DOI: 10.1016/j.atherosclerosis.2018.12.027
Abstract: BACKGROUND AND AIMS Calcification is a hallmark of advanced atherosclerosis and an active process akin to bone remodeling. Heparanase (HPSE) is an endo-β-glucuronidase, which cleaves glycosaminoglycan chains of heparan sulfate proteoglycans. The role of HPSE… read more here.
Keywords: human carotid; hpse expression; hpse; calcification ... See more keywords
Experimental evidence on colchicine's mode of action in human carotid artery plaques
Sign Up to like & getrecommendations! Published in 2024 at "European Heart Journal"
DOI: 10.1093/eurheartj/ehae666.3288
Abstract: Atherosclerosis driven by inflammation is a major cause of cardiovascular events. Recent clinical trials have demonstrated the therapeutic potential of anti-inflammatory treatments. Consequently, colchicine is recommended in current guidelines as a second-line therapy for secondary… read more here.
Keywords: colchicine; human carotid; evidence colchicine; experimental evidence ... See more keywords
Photothermal optical coherence microscopy for studying lipid architecture in human carotid arteries
Sign Up to like & getrecommendations! Published in 2024 at "Biomedical Optics Express"
DOI: 10.1364/boe.534800
Abstract: Photothermal optical coherence microscopy (PT-OCM) combines the high-resolution, label-free morphological imaging of OCM with the ability to discriminate tissue composition through phase-sensitive photothermal imaging. In this study, we perform 2D imaging of human carotid endarterectomies… read more here.
Keywords: human carotid; coherence microscopy; optical coherence; photothermal optical ... See more keywords
Frontotemporal dementia-associated protein "phosphorylated TDP-43" localizes to atherosclerotic lesions of human carotid and main cerebral arteries.
Sign Up to like & getrecommendations! Published in 2019 at "Histology and histopathology"
DOI: 10.14670/hh-18-140
Abstract: The transactivation response DNA binding protein (TARDP) of 43 kDa (TDP-43) is a nuclear protein pivotal in RNA processing. Because phosphorylated (p) TDP-43 has been identified as a component of ubiquitin-positive and tau-negative inclusions in… read more here.
Keywords: main cerebral; human carotid; tdp; carotid ... See more keywords
The human carotid atherosclerotic plaque: an observational review of histological scoring systems.
Sign Up to like & getrecommendations! Published in 2023 at "European review for medical and pharmacological sciences"
DOI: 10.26355/eurrev_202304_32179
Abstract: OBJECTIVE The atherosclerotic plaque is a complex dynamic pathological lesion of the arterial wall, characterized by multiple elementary lesions of different diagnostic and prognostic significance. Fibrous cap thickness, lipid necrotic core dimension, inflammation, intra-plaque hemorrhage… read more here.
Keywords: atherosclerotic plaque; review; plaque; carotid atherosclerotic ... See more keywords
Elevated Hepcidin Expression in Human Carotid Atheroma: Sex-Specific Differences and Associations with Plaque Vulnerability
Sign Up to like & getrecommendations! Published in 2024 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms25031706
Abstract: Hepcidin is upregulated by increased body iron stores and inflammatory cytokines. It is associated with cardiovascular events, arterial stiffness, and increased iron accumulation in human atheroma with hemorrhage. However, it is unknown whether the expression… read more here.
Keywords: hepcidin expression; human carotid; hepcidin; atheroma ... See more keywords