Potential Markers of Autoimmune Diseases, Alleles rs115662534(T) and rs548231435(C), Disrupt the Binding of Transcription Factors STAT1 and EBF1 to the Regulatory Elements of Human CD40 Gene
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DOI: 10.1134/s0006297918120118
Abstract: CD40 receptor is expressed on B lymphocytes and other professional antigen–presenting cells. The binding of CD40 to its ligand CD154 on the surface of T helper cells plays an important role in the activation of… read more here.
Keywords: cd40 gene; autoimmune diseases; cd40; human cd40 ... See more keywords
In silico binding analysis of human CD40 ligand mimetic molecule, 3-(dimethylamino)-1-phenyl-1-propanone hydrochloride (3-DPH), with CD40 receptor molecules of various mammalian species
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DOI: 10.22438/jeb/42/2/mrn-1440
Abstract: Aim: To investigate the binding of human CD40 ligand (CD40L) mimetic molecule, 3-(dimethylamino)-1-phenyl-1-propanone hydrochloride (3-DPH), with CD40 receptor (CD40R) molecules of Homo sapiens, Cavia porcellus, Cricetulus griseus, Macaca mulatta, Mus musculus, Oryctolagus cuniculus, Papio anubis… read more here.
Keywords: mimetic molecule; human cd40; mammalian species; cd40 ... See more keywords