Synthesis of N-aryl and N-alkyl substituted imidazolium silver complexes. Cytotoxic screening using human cell lines modelling acute myeloid leukemia.
Sign Up to like & getrecommendations! Published in 2020 at "ChemMedChem"
DOI: 10.1002/cmdc.202000138
Abstract: A series of N- aryl and N- alkyl substituted imidazoles were synthesized and complexed with Ag + to obtain silver-NHC complexes of the form [Ag(NHC)2 ]X. These silver-NHC complexes were tested in-vitro versus the human… read more here.
Keywords: alkyl substituted; cell lines; myeloid leukemia; aryl alkyl ... See more keywords
Neuroserpin regulates human T cell‐T cell interactions and proliferation through inhibition of tissue plasminogen activator
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Leukocyte Biology"
DOI: 10.1002/jlb.2a1019-098rr
Abstract: T cells play a key role in mounting an adaptive immune response. T cells are activated upon recognition of cognate Ag presented by an APC. Subsequently, T cells adhere to other activated T cells to… read more here.
Keywords: activation; biology; cell activation; proliferation ... See more keywords
Transduction of Human T Cell Subsets with Lentivirus.
Sign Up to like & getrecommendations! Published in 2021 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-1311-5_19
Abstract: Lentivirus-mediated gene transfer is an efficient method to introduce a variety of transgenes to human T cells. Here we describe a protocol to transduce human CD4+, CD8+, or CD4+ regulatory T cells. To illustrate the… read more here.
Keywords: cell subsets; regulatory cells; human cell; cell ... See more keywords
Production of Recombinant Factor VIII in Human Cell Lines.
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DOI: 10.1007/978-1-4939-7312-5_5
Abstract: Human cell lines can produce recombinant proteins much more similar to their natural counterpart, compared to other mammalian cell lines, reducing potential immunogenic reactions. Recombinant proteins produced in nonhuman cells can have in its structure… read more here.
Keywords: cell lines; recombinant factor; human cell; cell ... See more keywords
Oxidative Potential of Chemical Mixtures Extracted from Contaminated Galveston Bay, TX Seafood Using a Human Cell Co-culture Model
Sign Up to like & getrecommendations! Published in 2019 at "Archives of Environmental Contamination and Toxicology"
DOI: 10.1007/s00244-019-00695-w
Abstract: Increasing levels of pollution in Galveston Bay, TX, are of significant concern for populations that directly depend on fishing activities. Efforts to evaluate contaminant levels in commercial fish have been largely limited to the quantification… read more here.
Keywords: galveston bay; chemical mixtures; seafood; chemical ... See more keywords
Towards a surrogate system to express human lipid binding TCRs
Sign Up to like & getrecommendations! Published in 2019 at "Biotechnology Letters"
DOI: 10.1007/s10529-019-02713-2
Abstract: Previously we reported that natural nut lipids were necessary for sensitization and that natural killer T cells (NKTs) must play a critical role in the development of food allergic responses. A major bottleneck in further… read more here.
Keywords: system; human cell; surrogate system; cell ... See more keywords
Status of humoral and cellular immune markers in human T-cell lymphotropic virus type 1 (HTLV-1) asymptomatic carriers in northeastern Iran, Mashhad.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of neurovirology"
DOI: 10.1007/s13365-020-00910-8
Abstract: It is estimated that about 10-20 million peoples are infected with human T-cell leukemia virus type 1 (HTLV-1) around the world and suffered from HTLV-related diseases. The present study was aimed to evaluate the cellular… read more here.
Keywords: htlv; virus type; type htlv; htlv asymptomatic ... See more keywords
Myelopathy due to human T-cell leukemia virus type-1 from the donor after ABO-incompatible liver transplantation.
Sign Up to like & getrecommendations! Published in 2019 at "Annals of hepatology"
DOI: 10.1016/j.aohep.2018.06.002
Abstract: We report the case of a 53-year-old-man who developed human T-cell leukemia virus type-1-associated myelopathy (HAM) after ABO-incompatible liver transplantation for alcoholic liver cirrhosis. The living donor was seropositive for human T-cell leukemia virus type-1… read more here.
Keywords: leukemia virus; virus type; cell leukemia; transplantation ... See more keywords
High Frequency of Shared Clonotypes in Human T Cell Receptor Repertoires
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DOI: 10.1016/j.celrep.2020.107882
Abstract: SUMMARY The collection of T cell receptors (TCRs) generated by somatic recombination is large but unknown. We generate large TCR repertoire datasets as a resource to facilitate detailed studies of the role of TCR clonotypes… read more here.
Keywords: high frequency; frequency shared; human cell; shared clonotypes ... See more keywords
The antipsychotic drug pimozide is effective against human T-cell leukemia virus type 1-infected T cells.
Sign Up to like & getrecommendations! Published in 2021 at "European journal of pharmacology"
DOI: 10.1016/j.ejphar.2021.174373
Abstract: Patients with adult T-cell leukemia (ATL), caused by the human T-cell leukemia virus type 1 (HTLV-1), exhibit poor prognosis owing to drug resistance. Pimozide is a dopamine D2 receptor antagonist and antipsychotic shown to exhibit… read more here.
Keywords: cell leukemia; human cell; leukemia virus; cell ... See more keywords
The association of polymorphisms (rs2227981 and rs10204525) of PDCD1 gene with susceptibility to human T-cell leukemia virus type 1.
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DOI: 10.1016/j.micpath.2021.105049
Abstract: Human T-cell leukemia virus type 1 (HTLV-1) is the first retrovirus as the causative agent of two serious diseases in human is known. Programmed cell death-1 (PD-1) is a regulatory protein that has an important… read more here.
Keywords: virus type; cell leukemia; gene susceptibility; human cell ... See more keywords