A human-on-a-chip approach to tackling rare diseases.
Sign Up to like & getrecommendations! Published in 2019 at "Drug discovery today"
DOI: 10.1016/j.drudis.2019.08.001
Abstract: Drug development for rare diseases, classified as diseases with a prevalence of read more here.
Keywords: drug; human chip; chip approach; rare diseases ... See more keywords
Validation of an adipose-liver human-on-a-chip model of NAFLD for preclinical therapeutic efficacy evaluation
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-92264-2
Abstract: Nonalcoholic fatty liver disease (NAFLD) is the most common liver disease and strongly correlates with the growing incidence of obesity and type II diabetes. We have developed a human-on-a-chip model composed of human hepatocytes and… read more here.
Keywords: chip model; efficacy; model; evaluation ... See more keywords