The SSRI citalopram increases the sensitivity of the human circadian system to light in an acute dose
Sign Up to like & getrecommendations! Published in 2018 at "Psychopharmacology"
DOI: 10.1007/s00213-018-5019-0
Abstract: RationaleDisturbances of the circadian system are common in depression. Though they typically subside when depression is treated with antidepressants, the mechanism by which this occurs is unknown. Despite being the most commonly prescribed class of… read more here.
Keywords: human circadian; circadian system; sensitivity; citalopram ... See more keywords
The photobiology of the human circadian clock.
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2118803119
Abstract: SignificanceThe function of our biological clock is dependent on environmental light. Rodent studies have shown that there are multiple colors that affect the clock, but indirect measures in humans suggest blue light is key. We… read more here.
Keywords: photobiology human; photobiology; circadian clock; human circadian ... See more keywords
Duration invariance and intensity dependence of the human circadian system phase shifting response to brief light flashes
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the Royal Society B: Biological Sciences"
DOI: 10.1098/rspb.2021.1943
Abstract: The melanopsin-containing intrinsically photosensitive retinal ganglion cells (ipRGCs) are characterized by a delayed off-time following the cessation of light stimulation. Here, we exploited this unusual physiologic property to characterize the exquisite sensitivity of the human… read more here.
Keywords: circadian system; human circadian; phase; intensity ... See more keywords
Macroscopic Models for Human Circadian Rhythms
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Biological Rhythms"
DOI: 10.1177/0748730419878298
Abstract: Mathematical models have a long and influential history in the study of human circadian rhythms. Accurate predictive models for the human circadian light response have been used to study the impact of a host of… read more here.
Keywords: human circadian; circadian rhythms; experimental measurements; rhythms ... See more keywords
Circadian Photoentrainment in Mice and Humans
Sign Up to like & getrecommendations! Published in 2020 at "Biology"
DOI: 10.3390/biology9070180
Abstract: Light around twilight provides the primary entrainment signal for circadian rhythms. Here we review the mechanisms and responses of the mouse and human circadian systems to light. Both utilize a network of photosensitive retinal ganglion… read more here.
Keywords: circadian photoentrainment; human circadian; light; mice humans ... See more keywords
Sex differences and sex bias in human circadian and sleep physiology research
Sign Up to like & getrecommendations! Published in 2022 at "eLife"
DOI: 10.7554/elife.65419
Abstract: Growing evidence shows that sex differences impact many facets of human biology. Here we review and discuss the impact of sex on human circadian and sleep physiology, and we uncover a data gap in the… read more here.
Keywords: human circadian; circadian sleep; sex differences; sex ... See more keywords