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MLN4924 (Pevonedistat), a protein neddylation inhibitor, suppresses proliferation and migration of human clear cell renal cell carcinoma

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Published in 2017 at "Scientific Reports"

DOI: 10.1038/s41598-017-06098-y

Abstract: Neddylation is a post-translational protein modification associated with cancer development. MLN4924 is a neddylation inhibitor currently under investigation in multiple phase I studies on various malignancies, and its clincal name is Pevonedistat. It has been… read more here.

Keywords: mln4924; neddylation; migration; neddylation inhibitor ... See more keywords