A metabolomic evaluation of the phytochemical composition of tomato juices being used in human clinical trials.
Sign Up to like & getrecommendations! Published in 2017 at "Food chemistry"
DOI: 10.1016/j.foodchem.2017.01.118
Abstract: Juices from the traditional red tomato and a unique tangerine tomato variety are being investigated as health promoting foods in human clinical trials. However, it is unknown how the tangerine and red tomato juices differ… read more here.
Keywords: human clinical; tomato; metabolomic evaluation; clinical trials ... See more keywords
Sm-p80-Based Schistosomiasis Vaccine: Preparation for Human Clinical Trials.
Sign Up to like & getrecommendations! Published in 2017 at "Trends in parasitology"
DOI: 10.1016/j.pt.2016.10.010
Abstract: Mass antiparasitic drug administration programs and other control strategies have made important contributions in reducing the global prevalence of helminths. Schistosomiasis, however, continues to spread to new geographic areas. The advent of a viable vaccine… read more here.
Keywords: schistosomiasis; human clinical; schistosomiasis vaccine; clinical trials ... See more keywords
Protective Efficacy of Candidate Vaccines Prior to Human Clinical Trials.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of pharmaceutical sciences"
DOI: 10.1016/j.xphs.2018.08.005
Abstract: Immunization of animals is one of the key standards for evaluation of vaccine efficacy prior to human clinical trials. However, vaccine organizations should not over-interpret these results as protective efficacy in animals may not be… read more here.
Keywords: prior human; efficacy candidate; human clinical; protective efficacy ... See more keywords
Genomic description of human clinical Aspergillus fumigatus isolates, California, 2020
Sign Up to like & getrecommendations! Published in 2023 at "Medical Mycology"
DOI: 10.1093/mmy/myad012
Abstract: Abstract Aspergillus fumigatus, an environmental mold, causes life-threatening infections. Studies on the phylogenetic structure of human clinical A. fumigatus isolates are limited. Here, we performed whole genome sequencing of 24 A. fumigatus isolates collected from… read more here.
Keywords: genomic description; fumigatus isolates; aspergillus fumigatus; fumigatus ... See more keywords
Umbilical cord plasma concentrate has beneficial effects on DNA methylation GrimAge and human clinical biomarkers
Sign Up to like & getrecommendations! Published in 2022 at "Aging Cell"
DOI: 10.1111/acel.13696
Abstract: Plasma transfusions are standard treatments to replace missing proteins in people with rare genetic diseases. Prior studies have demonstrated that heterochronic parabiosis has beneficial effects on several tissues of old animals receiving young blood. Human… read more here.
Keywords: plasma concentrate; clinical biomarkers; umbilical cord; human clinical ... See more keywords
Epidemiology, Clinical Characteristics, and Antimicrobial Susceptibility Profiles of Human Clinical Isolates of Staphylococcus intermedius Group
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Clinical Microbiology"
DOI: 10.1128/jcm.01788-17
Abstract: ABSTRACT The veterinary pathogens in the Staphylococcus intermedius group (SIG) are increasingly recognized as causes of human infection. Shared features between SIG and Staphylococcus aureus may result in the misidentification of SIG in human clinical… read more here.
Keywords: staphylococcus intermedius; human clinical; sig isolates; intermedius group ... See more keywords
Development of a Genomics-Based Approach To Identify Putative Hypervirulent Nontyphoidal Salmonella Isolates: Salmonella enterica Serovar Saintpaul as a Model
Sign Up to like & getrecommendations! Published in 2022 at "mSphere"
DOI: 10.1128/msphere.00730-21
Abstract: Not all Salmonella isolates are equally likely to cause human disease, and Salmonella control strategies may unintentionally focus on serovars and subtypes with high prevalence in source populations but are rarely associated with human clinical… read more here.
Keywords: salmonella isolates; snp clusters; salmonella; human clinical ... See more keywords
Abstract CT056: The first-in-human clinical trial of MG7-CART for metastasis colon cancer
Sign Up to like & getrecommendations! Published in 2018 at "Cancer Research"
DOI: 10.1158/1538-7445.am2018-ct056
Abstract: MG7 antigen, a highly glycosylated CEACAM5 molecule, is specifically expressed in human gastrointestinal cancers. An MG7-CART therapy has been developed and showed great efficacy in gastric cancer PDX model. Here we present the first-in-human clinical… read more here.
Keywords: clinical trial; human clinical; mg7 cart; metastasis ... See more keywords
Data sharing platforms for de-identified data from human clinical trials
Sign Up to like & getrecommendations! Published in 2018 at "Clinical Trials"
DOI: 10.1177/1740774518769655
Abstract: Data sharing of de-identified individual participant data is being adopted by an increasing number of sponsors of human clinical trials. In addition to standardizing data syntax for shared trial data, semantic integration of various data… read more here.
Keywords: data sharing; research; sharing platforms; human clinical ... See more keywords
Vitamin C and the management of diabetic foot ulcers: a literature review.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of wound care"
DOI: 10.12968/jowc.2022.31.sup9.s33
Abstract: OBJECTIVE The lifetime risk of developing a diabetic foot ulcer (DFU) in people with diabetes is as high as 25%. A trio of factors constitute the diabetic foot syndrome that characterises DFUs, including neuropathy, vascular… read more here.
Keywords: diabetic foot; clinical trials; literature review; human clinical ... See more keywords
Analysis of human clinical and environmental Leptospira to elucidate the eco-epidemiology of leptospirosis in Yaeyama, subtropical Japan
Sign Up to like & getrecommendations! Published in 2022 at "PLoS Neglected Tropical Diseases"
DOI: 10.1371/journal.pntd.0010234
Abstract: Background Leptospirosis, a zoonosis caused by species in the spirochete genus Leptospira, is endemic to the Yaeyama region in Okinawa, subtropical Japan. Species of the P1 subclade “virulent” group, within the genus Leptospira, are the… read more here.
Keywords: leptospirosis; region; human clinical; yaeyama ... See more keywords