Immunohistochemical localization of Nrf2 in the human cochlea
Sign Up to like & getrecommendations! Published in 2018 at "Brain Research"
DOI: 10.1016/j.brainres.2018.07.004
Abstract: Oxidative stress plays an important role in several inner ear diseases and normal aging. Nuclear (erythroid-derived 2)-like 2, also known as Nrf2, is a transcription factor encoded by the NFE2L2 gene that controls the expression… read more here.
Keywords: human cochlea; immunohistochemical localization; localization nrf2; nrf2 human ... See more keywords
Super-resolution immunohistochemistry study on CD4 and CD8 cells and the relation to macrophages in human cochlea
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Otology"
DOI: 10.1016/j.joto.2018.11.010
Abstract: Recently, the human cochlea has been shown to contain numerous resident macrophages under steady-state. The macrophages accumulate in the stria vascularis, among the auditory nerves, and are also spotted in the human organ of Corti.… read more here.
Keywords: cd4 cd8; cd8 cells; super resolution; human cochlea ... See more keywords
Immunohistochemical localization of glucocorticoid receptors in the human cochlea
Sign Up to like & getrecommendations! Published in 2023 at "Brain Research"
DOI: 10.2139/ssrn.4159248
Abstract: In the present study we investigated the localization ofglucocorticoid receptors (GCR) in the human inner ear using immunohistochemistry. Celloidin-embedded cochlear sections of patients with normal hearing (n=5), patients diagnosed with MD (n=5), and noise induced… read more here.
Keywords: cell; gcr; localization; human cochlea ... See more keywords
Macrophages in the Human Cochlea: Saviors or Predators—A Study Using Super-Resolution Immunohistochemistry
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2018.00223
Abstract: The human inner ear, which is segregated by a blood/labyrinth barrier, contains resident macrophages [CD163, ionized calcium-binding adaptor molecule 1 (IBA1)-, and CD68-positive cells] within the connective tissue, neurons, and supporting cells. In the lateral… read more here.
Keywords: human cochlea; macrophages human; super resolution; microscopy ... See more keywords
Age-Related Changes in Immune Cells of the Human Cochlea
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Neurology"
DOI: 10.3389/fneur.2019.00895
Abstract: Age-related hearing loss is a chronic degenerative disorder affecting one in two individuals above the age of 75. Current population projections predict a steady climb in the number of older individuals making the search for… read more here.
Keywords: age related; age; human cochlea; auditory nerve ... See more keywords
Na/K-ATPase Gene Expression in the Human Cochlea: A Study Using mRNA in situ Hybridization and Super-Resolution Structured Illumination Microscopy
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Molecular Neuroscience"
DOI: 10.3389/fnmol.2022.857216
Abstract: Background The pervasive Na/K-ATPase pump is highly expressed in the human cochlea and is involved in the generation of the endocochlear potential as well as auditory nerve signaling and relay. Its distribution, molecular organization and… read more here.
Keywords: gene transcripts; microscopy; atpase; human cochlea ... See more keywords
Immunohistochemistry Reveals TRPC Channels in the Human Hearing Organ—A Novel CT-Guided Approach to the Cochlea
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24119290
Abstract: TRPC channels are critical players in cochlear hair cells and sensory neurons, as demonstrated in animal experiments. However, evidence for TRPC expression in the human cochlea is still lacking. This reflects the logistic and practical… read more here.
Keywords: trpc channels; channels human; immunohistochemistry reveals; reveals trpc ... See more keywords