Articles with "human colon" as a keyword



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SENP1 participates in Irinotecan resistance in human colon cancer cells

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Published in 2021 at "Journal of Cellular Biochemistry"

DOI: 10.1002/jcb.29946

Abstract: Colorectal cancer is one of the most prevalent cancers in the world. Chemoresistance has always been a problem encountered in its treatment. It is known that SUMOylation may regulate protein stability and decomposition, and even… read more here.

Keywords: senp1; cpt; colorectal cancer; human colon ... See more keywords
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Ebp1 p48 promotes oncogenic activities in human colon cancer cells through regulation of TIF‐90‐mediated ribosomal RNA synthesis

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Published in 2019 at "Journal of Cellular Physiology"

DOI: 10.1002/jcp.28385

Abstract: The ErbB3‐binding protein 1 (Ebp1) has been reported as either an oncogenic regulator or a tumor suppressor in a variety of cancers. Here, we show that Ebp1 p48, a predominant expression isoform, is highly expressed… read more here.

Keywords: oncogenic activities; colon; human colon; colon cancer ... See more keywords
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Antiproliferative Effect of Amaranth Proteins and Peptides on HT-29 Human Colon Tumor Cell Line

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Published in 2019 at "Plant Foods for Human Nutrition"

DOI: 10.1007/s11130-018-0708-8

Abstract: Antiproliferative effect of Amaranthus mantegazzianus proteins and peptides released after simulated gastrointestinal digestion (DH% 37.8 ± 3.8) was investigated on human colon cancer cell line HT-29. Inhibition of proliferation of HT-29 cells was exhibited after a 24 h… read more here.

Keywords: cell line; proteins peptides; antiproliferative effect; effect ... See more keywords
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Relation between structures of naphthalenylchalcone derivatives and their cytotoxic effects on HCT116 human colon cancer cells

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Published in 2018 at "Applied Biological Chemistry"

DOI: 10.1007/s13765-018-0356-6

Abstract: To find potent chemotherapeutic agents, cytotoxic effects of 42 synthetic chalcone derivatives bearing naphthyl groups on HCT116 human colon cancer cell lines were tested using the clonogenic long-term survival assay. The relationships between their half-maximal… read more here.

Keywords: cytotoxic effects; hct116 human; human colon; colon cancer ... See more keywords
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Synthesis and characterization of phenanthrene derivatives with anticancer property against human colon and epithelial cancer cell lines

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Published in 2017 at "Comptes Rendus Chimie"

DOI: 10.1016/j.crci.2017.03.008

Abstract: Abstract A variety of polycyclic aromatic hydrocarbons have been synthesized and structurally characterized in our laboratory. Phenanthrene derivatives were efficiently prepared in excellent yields and high purity via a two-step sequence. Heck coupling yielded the… read more here.

Keywords: cancer; phenanthrene derivatives; human colon; synthesis characterization ... See more keywords
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Short chain fatty acid butyrate uptake reduces expressions of prostanoid EP4 receptors and their mediation of cyclooxygenase‐2 induction in HCA‐7 human colon cancer cells

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Published in 2019 at "European Journal of Pharmacology"

DOI: 10.1016/j.ejphar.2019.04.014

Abstract: ABSTRACT Microbiota produce short chain fatty acids (SCFAs), which are known to maintain gut homeostasis, by the fermentation of dietary fiber in the human colon. Among SCFAs, butyrate has been considered as the most physiologically… read more here.

Keywords: ep4 receptors; butyrate uptake; human colon; cancer ... See more keywords
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Characterization of extractable components of fresh and fermented Huarong large-leaf mustard and their inhibitory effects on human colon cancer cells

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Published in 2021 at "Food bioscience"

DOI: 10.1016/j.fbio.2021.101280

Abstract: Abstract Leaf mustard is a popular cruciferous vegetable, and its chemical composition and biological activities have seldom been investigated. The aim of this study was to characterize the primary extractable components of fresh and fermented… read more here.

Keywords: mustard; inhibitory effects; leaf mustard; human colon ... See more keywords
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Rosemary (Rosmarinus officinalis L) extract increases ROS and modulates Nrf2 pathway in human colon cancer cell lines

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Published in 2017 at "Free Radical Biology and Medicine"

DOI: 10.1016/j.freeradbiomed.2017.04.263

Abstract: Carnosic acid, carnosol and betulinic acid are the main compounds present in rosemaryextract (RE) and have shown anti-proliferative effects on various tumor cell lines. The objective of this work was to study the anticancer effects… read more here.

Keywords: cell lines; nrf2 pathway; human colon; cancer cell ... See more keywords
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Ratiometric Detection of γ-Glutamyltransferase in Human Colon Cancer Tissues Using a Two-Photon Probe.

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Published in 2019 at "Analytical chemistry"

DOI: 10.1021/acs.analchem.9b02137

Abstract: γ-Glutamyltransferase (GGT) plays a role in cleaving the γ-glutamyl bond of glutathione. The GGT is known to be overexpressed in some tumors and has been recognized as a potential biomarker for malignant tumors. Colon cancer… read more here.

Keywords: two photon; colon; human colon; colon cancer ... See more keywords
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Protective Effects of Piceatannol on DNA Damage in Benzo[a]pyrene-Induced Human Colon Epithelial Cells.

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Published in 2023 at "Journal of agricultural and food chemistry"

DOI: 10.1021/acs.jafc.3c00874

Abstract: Evidence shows that the dietary intake of polycyclic aromatic hydrocarbons (PAHs) from food processing induces the cellular DNA damage response and leads to the development of colorectal cancer (CRC). Therefore, protecting from cellular DNA damage… read more here.

Keywords: benzo pyrene; damage; dna damage; human colon ... See more keywords
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PLEKHN1 promotes apoptosis by enhancing Bax-Bak hetro-oligomerization through interaction with Bid in human colon cancer

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Published in 2017 at "Cell Death Discovery"

DOI: 10.1038/s41420-017-0006-5

Abstract: The anti-apoptotic nature of cancer cells often impedes the effects of anti-cancer therapeutic agents. Multiple death signals influence mitochondria during apoptosis, and though many studies have attempted to elucidate these complicated pathways, Bax oligomerization, an… read more here.

Keywords: bax; plekhn1; human colon; bid ... See more keywords