Characterization of circular RNAs with advanced sequencing technologies in human complex diseases
Sign Up to like & getrecommendations! Published in 2022 at "Wiley Interdisciplinary Reviews: RNA"
DOI: 10.1002/wrna.1759
Abstract: Circular RNAs (circRNAs) are one category of non‐coding RNAs that do not possess 5′ caps and 3′ free ends. Instead, they are derived in closed circle forms from pre‐mRNAs by a non‐canonical splicing mechanism named… read more here.
Keywords: advanced sequencing; full length; complex diseases; circular rnas ... See more keywords
CSEA-DB: an omnibus for human complex trait and cell type associations
Sign Up to like & getrecommendations! Published in 2021 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkaa1064
Abstract: Abstract During the past decade, genome-wide association studies (GWAS) have identified many genetic variants with susceptibility to several thousands of complex diseases or traits. The genetic regulation of gene expression is highly tissue-specific and cell… read more here.
Keywords: type associations; cell; cell type; human complex ... See more keywords