Antitumor effects of novel mAbs against cationic amino acid transporter 1 (CAT1) on human CRC with amplified CAT1 gene
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DOI: 10.1111/cas.14741
Abstract: Copy number alterations detected by comparative genomic hybridization (CGH) can lead to the identification of novel cancer‐related genes. We analyzed chromosomal aberrations in a set of 100 human primary colorectal cancers (CRCs) using CGH and… read more here.
Keywords: cat1; cationic amino; crc; human crc ... See more keywords
JNK pathway plays a critical role for expansion of human colorectal cancer in the context of BRG1 suppression
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DOI: 10.1111/cas.15520
Abstract: Tumor stem cells (TSCs), capable of self‐renewal and continuous production of progeny cells, could be potential therapeutic targets. We have recently reported that chromatin remodeling regulator Brg1 is required for maintenance of murine intestinal TSCs… read more here.
Keywords: jnk pathway; brg1 suppression; human crc; suppression ... See more keywords