The human CSF pain proteome.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of proteomics"
DOI: 10.1016/j.jprot.2018.05.012
Abstract: Chronic pain represents one of the major medical challenges in the 21st century, affecting >1.5 billion of the world population. Overlapping and heterogenous symptoms of various chronic pain conditions complicate their diagnosis, emphasizing the need… read more here.
Keywords: protein; human csf; receptor; chronic pain ... See more keywords
The mechanism of GM-CSF inhibition by human GM-CSF auto-antibodies suggests novel therapeutic opportunities
Sign Up to like & getrecommendations! Published in 2018 at "mAbs"
DOI: 10.1080/19420862.2018.1494107
Abstract: ABSTRACT Granulocyte-macrophage colony-stimulating factor (GM-CSF) is a hematopoietic growth factor that can stimulate a variety of cells, but its overexpression leads to excessive production and activation of granulocytes and macrophages with many pathogenic effects. This… read more here.
Keywords: auto; human csf; csf auto; mechanism csf ... See more keywords
Gene Regulatory Network of Human GM-CSF-Secreting T Helper Cells
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Immunology Research"
DOI: 10.1155/2021/8880585
Abstract: GM-CSF produced by autoreactive CD4-positive T helper cells is involved in the pathogenesis of autoimmune diseases, such as multiple sclerosis. However, the molecular regulators that establish and maintain the features of GM-CSF-positive CD4 T cells… read more here.
Keywords: cd4 cells; human csf; gene regulatory; helper cells ... See more keywords
Quantitative profiling of endocannabinoids and related N-acylethanolamines in human CSF using nano LC-MS/MS[S]
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Lipid Research"
DOI: 10.1194/jlr.d070433
Abstract: Endocannabinoids, a class of lipid messengers, have emerged as crucial regulators of synaptic communication in the CNS. Dysregulation of these compounds has been implicated in many brain disorders. Although some studies have identified and quantified… read more here.
Keywords: endocannabinoids related; quantitative profiling; human csf; profiling endocannabinoids ... See more keywords