Insights into molecular mechanisms of drug metabolism dysfunction of human CYP2C9*30
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DOI: 10.1371/journal.pone.0197249
Abstract: Cytochrome P450 2C9 (CYP2C9) metabolizes about 15% of clinically administrated drugs. The allelic variant CYP2C9*30 (A477T) is associated to diminished response to the antihypertensive effects of the prodrug losartan and affected metabolism of other drugs.… read more here.
Keywords: cyp2c9; drug; human cyp2c9; molecular mechanisms ... See more keywords