Cryo-EM Structure of Human Dicer and Its Complexes with a Pre-miRNA Substrate
Sign Up to like & getrecommendations! Published in 2018 at "Cell"
DOI: 10.1016/j.cell.2018.03.080
Abstract: Human Dicer (hDicer) is a multi-domain protein belonging to the RNase III family. It plays pivotal roles in small RNA biogenesis during the RNA interference (RNAi) pathway by processing a diverse range of double-stranded RNA (dsRNA)… read more here.
Keywords: human dicer; pre mirna; cryo structure; hdicer ... See more keywords
ReCGBM: a gradient boosting-based method for predicting human dicer cleavage sites
Sign Up to like & getrecommendations! Published in 2021 at "BMC Bioinformatics"
DOI: 10.1186/s12859-021-03993-0
Abstract: Background Human dicer is an enzyme that cleaves pre-miRNAs into miRNAs. Several models have been developed to predict human dicer cleavage sites, including PHDCleav and LBSizeCleav. Given an input sequence, these models can predict whether… read more here.
Keywords: dicer cleavage; dicer; pre mirna; cleavage sites ... See more keywords