TRAF6 mediates human DNA2 polyubiquitination and nuclear localization to maintain nuclear genome integrity
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DOI: 10.1093/nar/gkz537
Abstract: Abstract The multifunctional human DNA2 (hDNA2) nuclease/helicase is required to process DNA ends for homology-directed recombination repair (HDR) and to counteract replication stress. To participate in these processes, hDNA2 must localize to the nucleus and… read more here.
Keywords: nuclear localization; human dna2; maintain nuclear; polyubiquitination ... See more keywords