Structure of human DPPA3 bound to the UHRF1 PHD finger reveals its functional and structural differences from mouse DPPA3
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DOI: 10.1038/s42003-024-06434-9
Abstract: DNA methylation maintenance is essential for cell fate inheritance. In differentiated cells, this involves orchestrated actions of DNMT1 and UHRF1. In mice, the high-affinity binding of DPPA3 to the UHRF1 PHD finger regulates UHRF1 chromatin… read more here.
Keywords: phd finger; uhrf1 phd; human dppa3; dppa3 ... See more keywords