Human DUX4 and porcine DUXC activate similar early embryonic programs in pig muscle cells: implications for preclinical models of FSHD.
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DOI: 10.1093/hmg/ddad021
Abstract: Human DUX4 and its mouse ortholog Dux are normally expressed in the early embryo-the 4-cell or 2-cell cleavage stage embryo, respectively-and activate a portion of the first wave of zygotic gene expression. DUX4 is epigenetically… read more here.
Keywords: porcine duxc; early embryonic; human dux4; muscle ... See more keywords